La PFNT (Plateforme NeuroTimone) est un ensemble cohérent d'outils d'exploration en neurobiologie permettant des investigations aux échelles moléculaires, cellulaires et intégrées.
La Plateforme INteractome Timone – PINT est heureuse de vous annoncer l’arrivée du Biacore T200 (Cytiva, ex GE Healthcare), système utilisant la technologie de SPR (Résonance Plasmonique de Surface) pour mesurer les interactions en temps réel entre biomolécules non marquées, des ions jusqu’aux virus. La mesure en temps réel permet d’obtenir les constantes cinétiques d’association (kon) et de dissociation (koff) et d’en déduire l’affinité (KD).
In this review, we focused on the most widely used 3D human glioblastoma models: spheroids, tumorospheres, organotypic slices, explants, tumoroids and glioblastoma-derived from cerebral organoids. We discuss their history, development and especially their usefulness.
We are very excited to announce that our project "Artificial Intelligence for Onco-Plasma" carried out by Remi Eyraud from QARMA team of LIS in collaboration with team 8, team 9, team 10, and PINT platform of INP, was awarded a grant from the MIC (Mathema
INP platform PINT together with AFMB and IMM are glad to announce their first inter-platform interactome workshop entitled "Methods to study Molecular Interactions (Biomedical applications)" that will take place from monday december 7th to friday 11th 2020.
Looking to confirm the interaction between a drug and its target?
Wanting to characterize the interaction between a receptor and its ligand?
Romain La Rocca, third year PhD student in INP team 9 (Cytoskeleton and Neurophysiopathology), will present a part of his thesis work during the 1st NanoTemper Virtual Symposium on June 30th from 9 to 12h30. NanoTemper annual seminars bring together the researchers using NanoTemper instruments, or eager to discover new technologies and in different fields of research. During this event, Romain will show how to use the nanoDSF technology to study the quaternary structure of tubulin.
Christophe Leterrier, leader of the NeuroCyto team, has just published "The Cell Biologist's Guide to Super-Resolution Microscopy", a poster and accompanying review article for the "At A Glance" series of the Journal of Cell Science. He teamed with Guillaume Jacquement and Hellyeh Hamidi from Turku University (Finland), Aexandre Carisey from the Baylor College of Medicine (Houston) and Ricardo Henriques from UCL/Crick Institute (London) to explain the principles and relative strenghts of the various super-resolution techniques hiding in a menagerie of acronyms (SIM, STED, STORM, SMLM...).
The Platform INteractome Timone - PINT is pleased to announce the arrival of the Tycho™ NT.6, the new nanoDSF instrument by Nanotemper. The Tycho is designed to characterize the quality of any protein within minutes, using only 10 µL of sample. This fast analysis is critical for choosing the batches, buffers, or conditions by comparing the relative stability of each sample along every step of an experiment, thus allowing an efficient assay and purification workflow development.
Since it requires just 10 µL of sample at a concentration anywhere from 0.01 to >200 mg/mL, it's not even necessary to dilute samples.
Christophe Leterrier, NeuroCyto team leader, will be one of the judges for the 46th Nikon Small World photomicrography and Small World in Motion video competitions. He will be the first French researcher to be on the judging panel for this prestigious competition.
L’INP figure en bonne place au palmarès du concours photo organisé par NeuroMarseille/NeuroSchool dont le but était de révéler la beauté du vivant à travers des images réalisées dans les laboratoires de neurosciences d’AMU. Huit laboratoires - INP, INT, IBDM, LNC, INMED, INS, LPC, CRMBM - ont envoyé des clichés (5 pour l’INP). Les 10 premières œuvres ont été sélectionnées et seront prochainement exposées dans une galerie de Marseille et une autre d’Aix en Provence. Celles non-retenues apparaîtront dans le catalogue imprimé de l’exposition.
The INP is proud to announce that, this year, four of its members have had their projects successfully granted by the French National Research agency (ANR - generic call 2021): Pascale Barbier (team 9), Christophe Leterrier (team 7), Emmanuel Nivet (team 6) and Aurélie Tchoghandjian (team 8).
La saison estivale est déjà amorcée, certains sont déjà en vacances (la chance !) et d'autres font de la résistance au labo. Le comité des fêtes de l'INP en a profité pour réunir les présents autour d'un pique-nique, juste avant le déménagement de l'équipe 8 !
Joyeuses vacances estivales à tous. Que nous revenions tous reposés, motivés et pleins d'ambitions et d'idées pour de belles recherches scientifiques à accomplir à la rentrée :-)
Vect-Horus and RadioMedix are pleased to announce the FDA clearance of exploratory Investigational New Drug (eIND) application to evaluate 68Ga-RMX-VH for the detection and mapping of Low Density Lipoprotein Receptor (LDLR) overexpressed in Glioblastoma Multiforme (GBM).
To learn more visit the article in the BUSINESS WIRE site
Last week the 8th annual seminar of Canceropole PACA took place in the Palais des Congrés of Saint Raphaël. During these 2 days a great number of scientific presentations were given, including different aspects of INP research coming from team 8, team 9 and the platform PINT, during the poster sessions.
La semaine dernière, vendredi 18 juin 2021, nous avons reçu la visite du Président de l’Université Eric Berton. Il était accompagné par la nouvelle Directrice Générale des Services de AMU Laurence Corvellec, le Doyen de la Faculté des Sciences Médicales et Paramédicales Georges Leonetti et l'assesseur à la Recherche la FSMP Jean Louis Mège.
Each week-end the local newspaper La Marseillaise puts the spotligh on a scientific topic and on a team of research in a scientific page called "Provence Terre de Science". After the page about Alzheimer disease last year (see here), INP research has been highligthed with the interview of Jean Marc Sabatier (Cytoskeleton and Neurophysiopathology team) for his work on venoms, and then Christophe Letterier (NeuroCyto team) for his work on sup