Plateforme NeuroTimone (PFNT)

La PFNT (Plateforme NeuroTimone) est un ensemble cohérent d'outils d'exploration en neurobiologie permettant des investigations aux échelles moléculaires, cellulaires et intégrées.

A la Une

  1. Fondation Vaincre Alzheimer's visit at the Institute of Neurophysiopathology (INP)

    A few weeks ago, the Vaincre Alzheimer Foundation came to visit the Institute of NeuroPhysiopathology and made a short documentary on the team Neural Plasticity and Degeneration (Team 1), led by Santiago Rivera who was recently funded by the Foundation. It was an opportunity for him to thank Vaincre Alzheimer and the donors and talk about the importance of MT5-MMP, a protease that contributes to the pathophysiological mechanisms of Alzheimer’s disease and may become a potential new target.

  2. MedIM 2020 : retour d'expérience

    Dans la semaine du lundi 07 décembre au vendredi 11 décembre s'est tenue avec succès la première édition de l'atelier MedIM (Methodes d'étude des Interactions Moléculaires) co-organisé par la Plateforme INteractome Timone (PINT) de l’INP, la plateforme de Biologie Structurale de l’AFMB et les plateformes de l’IMM, toutes trois labellisées "Plateformes Technologiques du site d'Aix-Marseille".

  3. New publication in Frontiers in Oncology
  4. The NeuroCyto team receives two ANR grants in 2020

    The NeuroCyto team led by Christophe Leterrier was awarded two collaborative ANR grants in the 2020 call. The first project, “How actin/spectrin scaffold shapes axonal physiology” (ASHA), is coordinated by C. Leterrier in collaboration with the teams of Stéphane Vassilopoulos (Institut de Myologie, Paris) and Emmanuel Nivet at INP.

  5. Laurie Arnaud (Team6) on the Neurobinar #3 (NeuroMarseille) !

    Laurie Arnaud will be presenting on the Neurobinar #3 on December 17 at 4 pm on Zoom.

    For this third edition, NeuroMarseille is pleased to welcome Christelle Baunez (INT), Laurie Arnaud (INP) and Nada El Mahmoudi (LNSC/LNC). Laurie Arnaud and Nada El Mahmoudi will introduce their respective theses in a cross presentation. After a question and answer session, Christelle Baunez (INT) will explain her research on the role of basal ganglia (GB) in motivation and reward processes.

  6. Dr. Emeline Tabouret (GlioME team) in collaboration with Dr. Rafael Arguello (CIML Institute) published a new paper in Cell metabolism journal

    This paper entitled "SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution" presents a new technique to study the metabolic responses in multiple cell types in parallel by flow cytometry.

  7. A successful partnership between the APHM Pathology department / the GlioME team and ID-Solutions industrial society.

    A successful partnership between the APHM Pathology department / the GlioME team and ID-Solutions industrial society (https://www.id-solutions.fr/fr/), has led to the developement of ready-to-use kits for the detection and quantification by digital PCR of key genetic alterations of brain tumours, specifically gliomas.

  8. Emeline TABOURET and Chiara BASTIANCICH recieved a grant of 30 000€ each

    Dr. Emeline Tabouret (MCU-PH) and Dr. Chiara Bastiancich (Post-doc) from the GlioME team received the "Emergence" grant co-funded by the Canceropôle PACA and the Association pour la Recherche sur les Tumeurs Cérébrales (ARTC-Sud).

    Dr. Tabouret wants to develop CAR-T cells directed against glioblastoma stem cells. The first step will be to design and then transfect the CARs into T cells and analyze their efficacy in vitro. The second step will consist of analyzing the in vivo efficacy of the CAR-T cells.

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L'INP en chiffres

  • 126 membres
  • 44 chercheurs
  • 48 chercheurs assistants
  • 12 post-doctorants
  • 11 doctorants

 

Romain La Rocca giving a talk in EuroTau 2021 meeting

Romain La Rocca, former member of INP team 9, shared the stage of EuroTau meeting in Lille's Grand Palais with Illana Gozes (Israel), Cláudio M. Gomes (Portugal), Amandine Grimm (Switzerland), Yann Fichou (France), Marina Rierola (Germany), Laura Vallés Saiz (Spain), Marie Galas (France) and Mahmoud Maina (UK / USA) during Session #3 chaired by Isabelle Landrieu & Yann Fichou.

He presented his PhD work on the Three zinc binding sites of Tau and their role in tau aggregation and little bit of the perspectives Dahbia Yatoui is currently working on right now.

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Emmanuel (Team 6) was an invited speaker at the French Club of Glial Cells meeting

On October, the 21st, Emmanuel was invited to give a talk during the 2021 meeting organized by the French Club of Glial Cells. Emmanuel had the chance to present the latest and exciting results of the NIVET team by giving a talk during a symposium dedicated on Glial cells in Brain diseases. Emmanuel's talk was entitled: "Human-iPSC-astrocytes reveal a pro-inflammatory axis under the control of the APOE4 genetic risk factor in Alzheimer's disease".

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Chiara Bastiancich lauréate de la bourse Élie Bzoura

Félicitations à Chiara Bastiancich, post-doctorante dans l'équipe GlioME qui a obtenu la bourse de recherche fondamentale Élie Bzoura 2021, délivrée par la Société Française de Pharmacie Oncologique et à l' Académie nationale de Pharmacie pour son projet GlioRET.

Congratulations to Chiara Bastiancich, post-doctoral fellow in the GlioME team who has been awarded the Élie Bzoura research grant by the French Society of Oncology Pharmacy and the French National Academy of Pharmacy for her GlioRET project.

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2 financements "Emergence" du Canceropole pour Aurélie Tchoghandjian et Gilles Breuzard

Aurélie Tchoghandjian (équipe 8 - GlioME) a obtenu un financement "Emergence" pour son projet intitulé "Création d’une lignée syngénique murine de cellules souches de glioblastome reproduisant l’hétérogénéité moléculaire et cellulaire des glioblastomes pour combattre la résistance thérapeutique" et Gilles Breuzard (équipe 9 - Cytosquelette et Physiopathologie) pour son projet intitulé "La protéine Tau comme nouvelle cible thérapeutique des glioblastomes : focus sur de nouveaux dérivés des thiazoloflavones "

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Welcome to Chisato, a new member of the Nivet team!

Our team is please to welcome Chisato Suematsu for a 6 months Master internship (from September 2021). Originated from Japan, Chisato is currently studying at the University of Oldenburg (Germany) where she is enrolled in the Neuroscience Program as a 2nd year master student. She is one of the 3 international students that have been selected by NeuroMarseille to receive a competitive fellowship in the context of the MSc incoming mobility 2021 call.

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Equipe 10 : nouvelle doctorante / Team 10 : New Phd

Après avoir effectué son stage de Master 2 sur le sujet régulation des facteurs de transcription de la famille FOXO par l’adrénomédulline dans les cellules endothéliales vasculaires, Norhimane  a rejoint l’équipe 10 en tant que doctorante à partir du 1er octobre 2021 grâce à une bourse de thèse financée par l’ARTC SUD. Elle mènera ses travaux de thèse sur la vaccination ciblée contre le système Adrenomédulline, une approche thérapeutique contre la croissance tumorale.

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