La PFNT (Plateforme NeuroTimone) est un ensemble cohérent d'outils d'exploration en neurobiologie permettant des investigations aux échelles moléculaires, cellulaires et intégrées.
Neural Plasticity and Degeneration team has recently welcomed Shweta SONAWANE.
Shweta is from Mumbai (India) she did her Ph.D. at the Biochemical sciences division of CSIR - National Chemical Laboratory in Pune (India).
Her doctoral research was largely focused on Tau pathology in Alzheimer’s disease studying in particular the effect of glycated and phosphorylated Tau on cytoskeleton integrity as well as aggregation propensity in order to find small molecules that could attenuate Tau aggregation and prevent its glycation.
The NeuroCyto team has a new publication out! Published on November 5th in Science, this article elucidates how adenosine A2A receptors drive removal of inhibitory synapses depending on their activity. This is a fruitful collaboration with the labs of Sabine Lévi at Institut du Fer à Moulin (IFM) in Paris and Christophe Bernard at Institut de Neuroscience des Systèmes (INS) in Marseille. Read the article here: https://www.science.org/doi/10.1126/science.abk2055
The NeuroCyto team has a new publication out! Published on Sep. 15 in Neuron, this article reveals how clathrin is slowly transported along axons by forming transport packets that are then docked at presynapses where they can dynamically supply clathrin for synaptic function. This is another episode of the long-standing collaboration between the NeuroCyto team and the lab of Subhojit Roy at UCSD. Read the article here: https://doi.org/10.1016/j.neuron.2021.08.016
Nadia Coliac a été l’auteure, metteuse en scène et scénographe d’une expérience théâtrale bioluminescente qui a eu lieu le 19 octobre dernier à Paris sur la scène des arts et des sciences du théâtre de la Reine Blanche. Une expérience grandeur nature d'éclairer tout un théâtre uniquement avec la lumière vivante qui a captivé le public, ce fut un moment magique !
Cette production artistique et scientifique fait partie de ses recherches dans le domaine de l'histoire des sciences pour réhabiliter la mémoire de " Raphaël Dubois génie de la lampe vivante".
PINT platform recently acquired the NT.Robotic Autosampler that complemented the existing Prometheus NT.Plex nanoDSF instrument which is already equipped with aggregation detection optics to get complete stability characterization.
NT.Robotic Autosampler is a stand-alone, all-inclusive system with robotic arm, computer, and monitor. PINT is now able to analyze up to 1,536 samples for hands-free characterization of thermal unfolding and chemical denaturation in a single experiment. Incorporate plate temperature control to keep your samples at 4 to 20 °C while they wait in the queue.
This will permit to scale up the existing applications of the Prometheus :
Romain La Rocca, former member of INP team 9, shared the stage of EuroTau meeting in Lille's Grand Palais with Illana Gozes (Israel), Cláudio M. Gomes (Portugal), Amandine Grimm (Switzerland), Yann Fichou (France), Marina Rierola (Germany), Laura Vallés Saiz (Spain), Marie Galas (France) and Mahmoud Maina (UK / USA) during Session #3 chaired by Isabelle Landrieu & Yann Fichou.
He presented his PhD work on the Three zinc binding sites of Tau and their role in tau aggregation and little bit of the perspectives Dahbia Yatoui is currently working on right now.
On October, the 21st, Emmanuel was invited to give a talk during the 2021 meeting organized by the French Club of Glial Cells. Emmanuel had the chance to present the latest and exciting results of the NIVET team by giving a talk during a symposium dedicated on Glial cells in Brain diseases. Emmanuel's talk was entitled: "Human-iPSC-astrocytes reveal a pro-inflammatory axis under the control of the APOE4 genetic risk factor in Alzheimer's disease".
Félicitations à Chiara Bastiancich, post-doctorante dans l'équipe GlioME qui a obtenu la bourse de recherche fondamentale Élie Bzoura 2021, délivrée par la Société Française de Pharmacie Oncologique et à l' Académie nationale de Pharmacie pour son projet GlioRET.
Congratulations to Chiara Bastiancich, post-doctoral fellow in the GlioME team who has been awarded the Élie Bzoura research grant by the French Society of Oncology Pharmacy and the French National Academy of Pharmacy for her GlioRET project.
On 19 and 20 May 2022 the GlioME team represented the INP at the "Brain tumor Meeting" in Berlin with the presentation of 6 posters:
- Chiara Bastiancich who won the 2nd poster prize: CHARACTERIZATION OF THE GLIOBLASTOMA RESECTION MICROENVIRONMENT AS THERAPEUTIC TARGET TOWARDS THE DEVELOPMENT OF LOCAL TREATMENT
Depuis janvier 2022, le Canceropôle a lancé les « Seminar Series ». Ces nouveaux rendez-vous mensuels d’une heure (13h-14h) permettent à un binôme de chercheurs (un.e expert.e niçois.e et un.e expert.e marseillais.e.) de présenter en visioconférence leurs sujets d’étude, projets, actualités… L'objectif étant d'animer la communauté de recherche en cancérologie et faire connaître les expertises des équipes de recherche de la région.
Le cinquième rendez-vous le mardi 31 mai 2022 de 13h à 14h, avec au programme :
Dominique Figarella-Branger, Carole Colin, Nathalie Baeza-Kallee and Aurélie Tchoghandjian have published a review on gliogenesis and the role of the ganglioside A2B5 is the gliomagenesis "A2B5 Expre
Chaque mois, NeuroMarseille publie sur son site internet les initiatives en développement durable (DD) d'un laboratoire de NeuroMarseille. Cette série est appelée "Green*tips" et donne la parole chaque mois à un·e référent·e du groupe de travail NeuroGreen de NeuroMarseille (9 laboratoires, plus ceux des équipes associées du MMG, de l’ISM et de l’institut Fresnel).
Du lundi 24 au vendredi 29 avril s'est tenue, toujours avec succès, la deuxième édition de la formation MedIM (Méthodes d'étude des Interactions Moléculaires) co-organisée par la Plateforme INteractome Timone (PINT) de l’INP, la plateforme de Biologie Structurale de l’AFMB et les plateformes de l’IMM, toutes trois labellisées "Plateformes Technologiques du site d'Aix-Marseille".