Plateforme NeuroTimone (PFNT)

La PFNT (Plateforme NeuroTimone) est un ensemble cohérent d'outils d'exploration en neurobiologie permettant des investigations aux échelles moléculaires, cellulaires et intégrées.

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  1. New preprint from the NeuroCyto team: tips and tricks for super-resolution microscopy

    We have a new preprint out! Want to do good super-resolution images? We have put together all our single molecule localization microscopy (SMLM) tips and tricks. This is a methods paper that describes our SMLM workflow, using benchmark samples such as microtubules and clathrin-coated pits. 

  2. Hotspots seen by STORM
    New publication from the NeuroCyto team in the Journal of Cell Biology: Slow axonal transport of actin via hotspots and trails

    Our latest work (previously on bioRxiv) is now published in the Journal of Cell Biology. We collaborated with the Roy lab (UW Madison, USA) and the Jung lab (Ohio University, USA) to reveal a new mechanism of slow axonal transport, based on our previous discovery of actin hotspots and trails

  3. Christophe at MiFoBio
    Christophe from the NeuroCyto team delivers plenary lecture at MiFoBio 2018

    Christophe was lucky to spend a whole week at the “Microscopie Fonctionnelle en Biologie” aka MiFoBio workshop. Lots of fun attending dozens of cutting-edge workshops, trying super-resolution microscopes, discussing, DJing (!), and presenting the latest work from the lab.

    More on Twitter: #MiFoBio2018

  4. The GlioME team has popularized a scientific article to make its research accessible to the general public.
  5. F. Devred presented PINT / INP work on a non-conventional use of nanoDSF at the ARBRE MOBIEU meeting
  6. Vect-Horus and RadioMedix announce signing of a Letter of Intent to co-develop a radio-theranostic agent for Glioblastoma
  7. Michel Khrestchatisky gives a talk at the « Nanomedicine for treating cancer and brain diseases » symposium
  8. Yvon Berland mentions Vect-Horus as one of the three 3 AMU biotech success stories

    In an interview published by "La Provence" on November 30, 2018 Yvon Bertrand, President of Aix-Marseille University, explains that AMU is very proud of its contribution to the field of Artificial Intelligence but also to the development of companies such as "First Light Imaging", VECT-HORUS or Innate-Pharma. They are real success stories from public research.

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L'INP en chiffres

  • 126 membres
  • 44 chercheurs
  • 48 chercheurs assistants
  • 12 post-doctorants
  • 11 doctorants

 

Hervé Kovacic élu président du CNU section 85

Professeur de Biophysique et Biomathématique à la Faculté de Pharmacie de Marseille, Hervé Kovacic est élu pour un mandat de six ans. La section CNU 85 gère les qualifications, promotions et primes des enseignant-chercheurs spécialisés en sciences physico-chimiques et ingénierie appliquée à la santé. Docteur Pascale Barbier, elle aussi membre de l'équipe 9 de l'INP a été nominé par le Ministère dans la même section CNU.

Français

Jean-Michel Paumier successfully defended his doctoral thesis

Jean-Michel Paumier, former PhD student in Team 1 (Neural Plasticity and Degeneration), has successfuly defended his thesis on Wednesday the 05th of December 2018. After few hours of a nice presentation followed by many questions, the examining board congratulated Jean-Michel for his good work and granted him the diploma of doctor in Neuroscience.

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Vect-Horus announces agreement with Johnson & Johnson innovation

Vect-Horus announced today the signing of a research collaboration agreement with Janssen Pharmaceuticals, Inc. one of the Janssen Pharmaceutical Companies of Johnson & Johnson. The goal of this collaboration is to use Vect-Horus’ proprietary technology to transport various Janssen monoclonal antibodies to the brain for the treatment of neurodegenerative diseases. This deal was facilitated by Johnson & Johnson Innovation Limited.

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New article from the Neural Degeneration and Plasticity team

The latest work from the Neural Degeneration and Plasticity team, in collaboration with the BBB and neuroinflammation team of Michel Khrestchatisky: "The pro-amyloidogenic effects of Membrane-type 1-Matrix Metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP trafficking" is now published in the FASEB Journal (doi: 10.1096/fj.201801076R).

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Yvon Berland and Alexandre Tokay, respectively President of AMU and CEO of Vect-Horus signed a Public-Private Partnership allowing Vect-Horus to settle its research activities in the La Timone Medical Faculty

Vect-Horus has established a long-term highly efficient collaboration with the Institute of NeuroPhysiopathology INP (UMR7051 CNRS-AMU) directed by Dr. Michel KHRESTCHATISKY, cofounder of the company, and this Partnership signed on November 14, 2018 is a cornerstone in the creation of the LABCOM (Common Research Lab) between the INP and Vect-Horus.

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New article from the NeuroCyto Team: Slow axonal transport of actin via hotspots and trails

The latest work of the NeuroCyto Team (previously on bioRxiv) is now published in the Journal of Cell Biology. We collaborated with the Roy lab to reveal a new mechanism of slow axonal transport, based on the previous discovery of actin hotspots and trails. Hotspots are static actin clusters that appear and disappear within minutes every 3-4 µm along the axon.

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Details of hotspots seen by STORM

1st Congress of the 7 CoENs (International Network of Centers of Excellence in Neurodegeneration)

Santiago Rivera represented the INP on the 1st Congress of the 7 CoENs (International Neetwork of Centers of Excellence in Neurodegeneration) held in Montpellier on October 18 and 19, 2018, endorsed by AVIESAN: Bordeaux, Grenoble, Lille, Montpellier, Marseille, Paris and Toulouse. He gave a lecture in the CoEN Pathfinder laureates’ session entitled MT-MMPs at the crossroads of amyloidogenesis and neuroinflammation in Alzheimer's disease.

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