NeuroTimone Facility (PFNT)

The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.

News

  1. Logo PFNT
    Le label « Plateforme Technologique Aix-Marseille » de la PlateForme NeuroTimone PFNT a été renouvelé

    Le label « Plateforme Technologique Aix-Marseille » de la PlateForme NeuroTimone PFNT a été renouvelé pour une nouvelle période de 3 ans par AMU, l’Inserm et le CNRS. Pour mémoire rappelons que la PFNT est constituée des plateformes NCIS, PINT et SCeNT de l’INP et de INPHIM de l’INT. La PFNT offre un éventail de prestations technologiques en neurobiologie au niveau local pour les équipes de recherche et start up de Marseille mais aussi au niveau régional et national.

  2. Performance théatralisée en hommage à Raphaël Dubois
  3. dianette akta Geraldine biacore
    PINT new acquisitions: Biacore T200 & AKTA pure

    The Platform INteractome Timone - PINT is pleased to announce the arrival of a brand new Surface Plasmon Resonance Biacore T200 (Cytiva, ex GE Healthcare) designed to follow in real time interactions between free-labeled biomolecules from ions to viruses. The use of real-time measurement allows to provide association (kon) and dissociation (koff) rate constant of the interaction and to deduce its affinity (KD).

  4. The GlioME team published a review on preclinical human 3D glioblastoma models

    In this review, we focused on the most widely used 3D human glioblastoma models: spheroids, tumorospheres, organotypic slices, explants, tumoroids and glioblastoma-derived from cerebral organoids. We discuss their history, development and especially their usefulness.

  5. INP teams awarded MIC Cancer Inserm - ITMO Aviesan 2020 grant
  6. MedIM 2020 : First inter-platform Interactome workshop

    INP platform PINT together with AFMB and IMM are glad to announce their first inter-platform interactome workshop entitled "Methods to study Molecular Interactions (Biomedical applications)" that will take place from monday december 7th to friday 11th 2020. 

    Looking to confirm the interaction between a drug and its target?
    Wanting to characterize the interaction between a receptor and its ligand?

  7. New publication of the GlioME team.

    In this paper we reported two uncommon adult cases of Diffuse Leptomeningeal Glioneuronal Tumors (DLGNTs) diagnosed after DNA-methylation profiling. This study enlarges the clinical and molecular spectrum of DLGNTs which encompass a wide spectrum of tumors that has yet to be fully clarified, and suggest that this terminology appears unsuitable in some cases. These tumors would be further classified in the large group of “gliomas and glioneuronal tumors driven byMAP-Kinase pathway alterations” in the fifth edition of the WHO classification of CNS tumors that is coming soon.

     

  8. Nanotemper Technologies 1st Virtual Symposium 

    Romain La Rocca, third year PhD student in INP team 9 (Cytoskeleton and Neurophysiopathology), will present a part of his thesis work during the 1st NanoTemper Virtual Symposium on June 30th from 9 to 12h30. NanoTemper annual seminars bring together the researchers using NanoTemper instruments, or eager to discover new technologies and in different fields of research. During this event, Romain will show how to use the nanoDSF technology to study the quaternary structure of tubulin. 

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INP in numbers

  • 126 members
  • 44 researchers
  • 48 research assistants
  • 12 post-docs
  • 11 PhD

 

Participation de Chiara BASTIANCICH à "la nuit européenne des chercheurs"

Chiara, post-doctorante dans l'équipe 8 a participé au "Speed-Searching 2.0" à l'occasion de la nuit européenne des chercheurs 2021. Chiara a rencontré virtuellement 6 groupes de 4-5 personnes avec qui elle a échangé sur son parcours de pharmacienne et le développement de sa thématique de recherche "Traitement local à base de nanomédicament pour le glioblastome".

Chacun de ces groupes a pu comprendre les avantages et inconvénients de ces traitements à travers deux objets :

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INP revealing "The Beauty of Life"

The INP is one of the winners of the photo contest organized by NeuroMarseille/NeuroSchool. The goal of the contest was to reveal the "beauty of life" through images taken in the neuroscience laboratories of AMU. Eight laboratories - INP, INT, IBDM, LNC, INMED, INS, LPC, CRMBM - sent pictures (5 for INP). The first 10 works have been selected and will soon be exhibited in a gallery in Marseille and another in Aix en Provence. Those not selected will appear in the printed catalog of the exhibition.

English

INP 2021 ANR awards

The INP is proud to announce that, this year, four of its members have had their projects successfully granted by the French National Research agency (ANR - generic call 2021): Pascale Barbier (team 9), Christophe Leterrier (team 7), Emmanuel Nivet (team 6) and Aurélie Tchoghandjian (team 8).

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Pique nique à l'INP avant les vacances !

La saison estivale est déjà amorcée, certains sont déjà en vacances (la chance !) et d'autres font de la résistance au labo. Le comité des fêtes de l'INP en a profité pour réunir les présents autour d'un pique-nique, juste avant le déménagement de l'équipe 8 !

Joyeuses vacances estivales à tous. Que nous revenions tous reposés, motivés et pleins d'ambitions et d'idées pour de belles recherches scientifiques à accomplir à la rentrée :-) 

 

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Dominique Figarella-Branger from the GlioME Team 8 has been involved in the fifth edition of the WHO Classification of Tumors of the Central Nervous System

The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS), is the sixth version of the international standard for the classification of brain and spinal cord tumors. Building on the 2016 updated fourth edition and the work of the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW), the 2021 fifth edition introduces major changes that advance the role of molecular diagnostics in CNS tumor classification.

 

English

Vect-Horus and RadioMedix Announce FDA Approval of Exploratory IND of Diagnostic 68 Ga-RMX-VH in Glioblastoma Multiforme

Vect-Horus and RadioMedix are pleased to announce the FDA clearance of exploratory Investigational New Drug (eIND) application to evaluate 68Ga-RMX-VH for the detection and mapping of Low Density Lipoprotein Receptor (LDLR) overexpressed in Glioblastoma Multiforme (GBM).

To learn more visit the article in the BUSINESS WIRE site

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Retour sur la visite du Président Eric Berton le 18 juin 2021

La semaine dernière, vendredi 18 juin 2021, nous avons reçu la visite du Président de l’Université Eric Berton. Il était accompagné par la nouvelle Directrice Générale des Services de AMU Laurence Corvellec, le Doyen de la Faculté des Sciences Médicales et Paramédicales Georges Leonetti et l'assesseur à la Recherche la FSMP Jean Louis Mège.

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2 INP researchers in La Marseillaise "Provence Terre de Science" 

Each week-end the local newspaper La Marseillaise puts the spotligh on a scientific topic and on a team of research in a scientific page called "Provence Terre de Science". After the page about Alzheimer disease last year (see here), INP research has been highligthed with the interview of Jean Marc Sabatier (Cytoskeleton and Neurophysiopathology team) for his work on venoms, and then Christophe Letterier (NeuroCyto team) for his work on sup

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