LOUIS Laurence
Onglets principaux
Publications
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Mutations in specific domains of MT5-MMP prevent the accumulation of toxic APP metabolites and serve as templates for peptide-based therapeutics in human in vitro models of Alzheimer's disease2024
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Suppression of MT5-MMP reveals early modulation of Alzheimer’s pathogenic events in primary neuronal cultures of 5xFAD mice2024
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MT5-MMP promotes neuroinflammation, neuronal excitability and Aβ production in primary neuron/astrocyte cultures from the 5xFAD mouse model of Alzheimer’s diseaseJournal of Neuroinflammation2022
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The C-terminal of MT5-MMP regulates C99 processing and Aβ levels in a cell model of Alzheimer's disease2022
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MT5-MMP promotes neuroinflammation, neuronal excitability and Aβ production in primary neuron/astrocyte cultures from the 5xFAD mouse model of Alzheimer's diseaseJournal of Neuroinflammation2022
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MT5-MMP is a modulator of inflammation: a study in murine and human neural cells related to Alzheimer’s disease2021
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MT5‐MMP controls APP and β‐CTF/C99 metabolism through proteolytic‐dependent and ‐independent mechanisms relevant for Alzheimer's diseaseFASEB Journal2021
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Human iPSCs-derived astrocytes reveal APOE as a critical modulator of inflammation that could underlie Alzheimer’s disease pathogenesis2021
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MT5-MMP at the crossroads of neuroinflammation and amyloidogenesis: study in murine and human neural cells2021
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MT5-MMP controls APP and β-CTF/C99 metabolism through proteolytic-dependent and -independent mechanisms relevant for Alzheimer’s disease2020
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Proamyloidogenic effects of membrane type 1 matrix metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP traffickingFASEB Journal2019
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Propolis potentiates the effect of cranberry (Vaccinium macrocarpon) against the virulence of uropathogenic Escherichia coliScientific Reports2018
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Biogenesis of Pro-senescent Microparticles by Endothelial Colony Forming Cells from Premature Neonates is driven by SIRT1-Dependent Epigenetic Regulation of MKK6Scientific Reports2017
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Evidence for an important role of host microRNAs in regulating hepatic fibrosis in humans infected with &ITSchistosoma japonicum&ITInternational Journal for Parasitology2017
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Gene Expression Analysis Reveals Genes Common to Cerebral Malaria and Neurodegenerative DisordersJournal of Infectious Diseases2017
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Whole genome Cardiac DNA methylation fingerprint and gene expression analysis provide new insights in the pathogenesis of Chronic Chagas disease CardiomyopathyClinical Infectious Diseases2017
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The Transcriptional Effects of PCB118 and PCB153 on the Liver, Adipose Tissue, Muscle and Colon of Mice: Highlighting of Glut4 and Lipin1 as Main Target Genes for PCB Induced Metabolic DisordersPLoS ONE2015
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Novel complex phenomena in ferroelectric nanocompositesJournal of Physics: Condensed Matter2012
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Low-Symmetry Phases in Ferroelectric NanowiresNano Letters2010
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Anisotropy of magnetci susceptibility and P-wave velocity in core samples from the Taïwan Chelungpu-fault drilling project (TCDP)Journal of Structural Geology2008
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Evolution of fractures patterns and anisotropic physical properties of rocks in Ramp-related folds. In : R. Swennen, F. Roure and J.W. Granath (eds). Deformation, fluid flow and reservoir appraisal in foreland fold and thrust beltsAAPG Hedberg Series2004
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Evolution of Fracture Patterns and Physical Properties of Rocks in the Chaudrons Ramp-related Anticline (Corbières, France). In R. Swennen, F. Roure and J.W. Granath eds, Deformation, fluid flow and reservoir appraisal in foreland and thrust beltsAAPG Bulletin2004
