The Institute of NeuroPhysiopathology (INP) is a training and research centre of excellence that combines basic and translational research to study neural cell organisation, function and interaction, the molecular and cellular bases of major brain diseases, and to develop innovative cellular and molecular therapeutic strategies.
Teams
NeuroTimone Facility (PFNT)
The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.
News
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Two new papers recently published by the GlioME teamChiara Bastiancich, Florian Correard and Marie-Anne Estève published two papers on glioblastoma therapy.
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Laurie Arnaud from Team 1&6 has won the "Young Researcher Prize" for her poster presentation at the 4th edition of CALM 2020, organized by the Club Alzheimer de MontpellierWe are proud to announce that Laurie Arnaud, the third year PhD student in INP's Teams 1 and 6 (Neural Plasticity and Degeneration & Stem cells, Disease modeling and Neuroregeneration), recently won the Best Poster presentation prize at CALM 2020, the 4th edition, organized by the Club Alzheimer de Montpellier on the 17 and 18 of November 2020. She presented her work intitulated "Regulation of astrocyte inflammation by Apolipoprotein E (APOE): demonstration of an NF-kB-dependent mechanism mediated by a newly identified partner".
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Semaine du cerveau 2021 : Notre cerveau : des neurones… et quoi d’autre ?La 22ème édition de la « Semaine du Cerveau » s’adapte à la pandémie ! Plusieurs chercheurs de l’INP (Caroline Strube, Olivier Bosler et Anne-Marie François-Bellan) membres de l’association « cerveau point comm » participent à l’organisation au niveau régional de la Semaine du Cerveau, une manifestation internationale grand public coordonnée en France par la Société des Neurosciences.
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L'équipe GlioME fière de la nomination de Chiara Bastiancich au Prix Départemental pour la recherche, section Jeune ChercheurMardi 16 février 2021, Chiara Bastiancich, Post-doc dans l'équipe GlioME faisait partie des 3 nominés en lice pour le prix "Jeune Chercheur" au 5ème Prix Départemental de la recherche en Provence organisé par le Département des Bouches du Rhône.
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Dominic Bingham (NeuroCyto team) at Neurobinar #5On February 18 at 4 pm, come and discover the work of Pierre-Yves Jacob (LNC), Lucas Goirand-Lopez (INMED) and Dominic Bingham (INP, NeuroCyto team). Dominic Bingham and Lucas Goirand-Lopez will introduce their respective PhD in a cross-presentation. After a question session for PhD students, Pierre-Yves Jacob will share with us his research on the brain network underlying spatial navigation (displacement, orientation) in complex environments.
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De "nouvelles têtes" dans l'équipe GlioME !L'équipe GlioME a le plaisir d'accueillir actuellement 3 nouveaux étudiants (de gauche à droite sur la photo):
- Victoria Hein, doctorante en 1ère année, qui débute sa thèse sur le thème "Cellules souches de glioblastome et gangliosides : vers de nouvelles approches thérapeutiques", co-encadrée par Emeline Tabouret et Dominique Figarella-Branger.
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Christophe Leterrier (NeuroCyto team) in Nature MaterialsChristophe Leterrier from the NeuroCyto team just published a study in collaboration with the Cytomorpho lab - Manuel Théry & Laurent Blanchoin, CEA Paris/Grenoble. Entitled “Self-repair protects microtubules from destruction by molecular motors”, this work demonstrates how motor proteins kinesins and dynein can damage microtubule while walking on them, triggering repair by incorporation of new tubulin monomers inside the microtubule lattice. It was published on Jan.
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Dominika Pilat (Team 1) on the Neurobinar #4 (NeuroMarseille) !Dominika Pilat will be presenting on the Neurobinar #4 on January 21 at 4 pm on Zoom.
For this fourth edition, NeuroMarseille is pleased to welcome Cédric Maurange (IBDM), Dominika Pilat (INP) and Borloz Émilie (MMG). Dominika Pilat and Borloz Émilie will introduce their respective theses in a cross presentation. After a question session, Cédric Maurange (IBDM) will explain his research on genetic programmes modifying the properties of neural stem cells during development.
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INP in numbers
- 126 members
- 44 researchers
- 48 research assistants
- 12 post-docs
- 11 PhD
Welcome to Guillaume, a new Master 2 student in the Nivet Team!
We are please to welcome Guillaume Benhora-Chabeaux for his 5-month Master internship (2nd year) in the Nivet team. After obtaining a first Master degree in Cognitive Science (MASCO) from the Aix-Marseille University, with the highest honours, Guillaume has enrolled the Master in Neuroscience (cellular and molecular neuroscience). Guillaume will be working on the crosstalk between inflammation and a susceptibility to neurodegeneration using in vitro and in vivo models.
Emmanuel Nivet (Team 6) is a new member of the European Scientific Advisory Board
Dr Emmanuel Nivet has been appointed as a new member of the European Scientific Advisory Board (SAB) of a joint organization unifying the Alzheimer Forschung Initiative e.V. (AFI), Germany, Alzheimer Nederland (AN), The Netherlands and Fondation Vaincre Alzheimer (FVA), France. Each of the above organizations is dedicated to funding dementia research in its own country.
Zoom sur la 5ème édition de la classification de l'OMS des tumeurs du Système Nerveux Central
Membre expert du comité éditorial et co-auteur de plusieurs chapitres de la 5ème édition de la Classification des tumeurs du SNC de l’OMS parue le 12 novembre dernier, Dominique Figarella-Branger (Equipe 8 GlioME) a dirigé la rédaction d'un article de revue en français sur cette nouvelle classification, récemment publié dans les Annales de Pathologie: https://authors.elsevier.com/c/1eB1VtB1GOhjB
Dominika Pilat (team 1) PhD defense
Recent works on Zinc binding to S100A1 and to NCS-1 published in Biomolecules and in International Journal of Molecular Sciences respectively
Team 9 (Cytoskeleton and Neurophysiopathology) and platform PINT (platform interactive Timone) are happy to see the almost simultaneous publications of two papers about about the impact of Zn2+ binding to NCS1 and to S100A1 respectively with their collaborators from Belozersky Institute of Physico Chemical Biology, Lomonosov Moscow State University, while the third one about Tau protein Zn2+ binding sites has been under review for already 3 months ...
Poste pourvu : Ingénieur - CDD de 12 mois
Mission : Etudier le rôle des gènes X et Z dans l’agressivité et la résistance au traitement du glioblastome
Etablissement d’accueil : Equipe 8 GlioME (Gliomagenèse et MicroEnvironnement) – Institut de Neurophysiopathologie - Faculté de Médecine Timone - MARSEILLE
Site web : https://inp.univ-amu.fr/en/teams/gliome-gliomagenesis-and-microenvironment
Tau & Glioma : new article from INP team 9 and team 8 in Cancers
The Cytoskeleton & Neurophysiopathology team and the GlioME team have a new publication out! Published on November 19th in Cancers, this article gives insights into how Tau regulates glioblastoma progression, via the PI3K-AKT signaling pathway.
Read the article here: https://www.mdpi.com/2072-6694/13/22/5818
INP participation to AMU's 1st Digital Sciences and AI for Health conference
On November 25 and 26, the conference "Digital Sciences and Artificial Intelligence for Health at Aix-Marseille University" was held in the Grisoli amphitheater & the Great Hall of the Faculty of Medical and Paramedical Sciences - Timone.
The aim of this conference was to formally bring together for the first time all the actors of Aix-Marseille University and the University Hospital Center involved in the digital and AI/health field, whether they are clinicians or theoreticians.
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