An article entitled "Le CNRS et Aix-Marseille Université signent un accord avec la PME Vect-Horus sur la propriété intellectuelle",  published in the CNRS Innovation Letter of 20 June 2019 and relayed by the INSB site, features the agreement signed by CNRS, AMU and Vect-Horus establishing the intellectual property rights regime and the exploitation of patents.

Our last work on IAPs : "Inhibitor of Apoptosis Proteins (IAPs) Determines Glioblastoma Stem‐Like Cell Fate in an Oxygen‐Dependent Manner" is now published in Stem Cells. We highlighted that pharmacological inhibition of IAPs by Smac mimetic GDC-0152 was able to decrease glioblastoma stem-like cells viability in hypoxia by decreasing cell proliferation and increasing apoptosis through ATR and TNFα pathways

During the last NeuroFrance congress held from May 22 to 24, 2019 at the Palais des Congrès in Marseille, the INP distinguished itself through 20 posters, 4 oral communications, and 1 symposium moderation, not to mention the organization of the "Art in Mind" exhibition, showing not only the richness and quality of his research but also his open-mindedness. 

In the CNRS Innovation Letter of April, there is an article entitled "Des molécules vectorisées pour cibler les maladies neurodégénératives" featuring the research collaboration agreement signed by Vect-Horus and Johnson & Johnson subsidiary Janssen Pharmaceuticals for treating neurodegenerative diseases.

On the 26-31st March, the 14th International Conference on Alzheimer's and Parkinson's Diseases (ADPD) and related neurological disorders was held in Lisbon, Portugal.

The LEGO Pumpy (or more officially NanoJ-Fluidics) paper is out in Nature Communications! A joint venture between the INP NeuroCyto team and the Henriques lab, this article (previously available as a preprint on bioRxiv) details how to build a fully open-source multi-channel syringe pumps with LEGO and Arduino.

We have a new preprint out! Want to do good super-resolution images? We have put together all our single molecule localization microscopy (SMLM) tips and tricks. This is a methods paper that describes our SMLM workflow, using benchmark samples such as microtubules and clathrin-coated pits. 

Our latest work (previously on bioRxiv) is now published in the Journal of Cell Biology. We collaborated with the Roy lab (UW Madison, USA) and the Jung lab (Ohio University, USA) to reveal a new mechanism of slow axonal transport, based on our previous discovery of actin hotspots and trails. 

Christophe was lucky to spend a whole week at the “Microscopie Fonctionnelle en Biologie” aka MiFoBio workshop. Lots of fun attending dozens of cutting-edge workshops, trying super-resolution microscopes, discussing, DJing (!), and presenting the latest work from the lab.

More on Twitter: #MiFoBio2018

The popularization of science is one of the missions of academic research. This article authored by Aurélie Soubéran is intended for children aged 12-13 years and more broadly for the general public, and focuses on a preclinical study on glioblastoma model.

To access it, please download the pdf version.