NeuroTimone Facility (PFNT)

The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.

News

  1. F. Devred and E. Tabouret presented their research work at the annual Canceropole PACA meeting
  2. INP team 8 and 9 and PINT members presented their work at the 4th French Microtubule Network

    INP team 8 and 9 and PINT members being part of the French Microtubule Network, several members presented their work at the 4th French Microtubule Network gathering in Rennes on the 1srt and 2nd july 2019, in the  "Microtubules and their regulators : new therapeutic targets" session and the "Microtubules, assembly and regulation" session. Pascale Barbier presented her work "", Raphael Berges his work "Proscillaridin A exerts anti-tumor effects through"GSK3 activation and alteration of microtubule dynamics in glioblastoma" and François Devred a new method of "Functional screening of therapeutic agents and targets using nanoDSF "

  3. CNRS and Aix-Marseille University sign Agreement with the SME Vect-Horus on the intellectual property

    An article entitled "Le CNRS et Aix-Marseille Université signent un accord avec la PME Vect-Horus sur la propriété intellectuelle",  published in the CNRS Innovation Letter of 20 June 2019 and relayed by the INSB site, features the agreement signed by CNRS, AMU and Vect-Horus establishing the intellectual property rights regime and the exploitation of patents.

  4. The GlioME team published a new article in Stem Cells and one eye-catch figure of their paper was selected for the cover image of the June journal issue!

    Our last work on IAPs : "Inhibitor of Apoptosis Proteins (IAPs) Determines Glioblastoma Stem‐Like Cell Fate in an Oxygen‐Dependent Manner" is now published in Stem Cells. We highlighted that pharmacological inhibition of IAPs by Smac mimetic GDC-0152 was able to decrease glioblastoma stem-like cells viability in hypoxia by decreasing cell proliferation and increasing apoptosis through ATR and TNFα pathways

  5. INP researchers and students massively attended NeuroFrance 2019

    During the last NeuroFrance congress held from May 22 to 24, 2019 at the Palais des Congrès in Marseille, the INP distinguished itself through 20 posters, 4 oral communications, and 1 symposium moderation, not to mention the organization of the "Art in Mind" exhibition, showing not only the richness and quality of his research but also his open-mindedness. 

  6. The CNRS features Vect-Horus and the INP in the Innovation Letter of April

    In the CNRS Innovation Letter of April, there is an article entitled "Des molécules vectorisées pour cibler les maladies neurodégénératives" featuring the research collaboration agreement signed by Vect-Horus and Johnson & Johnson subsidiary Janssen Pharmaceuticals for treating neurodegenerative diseases.

  7. INP students presented their research work at the 14th International Conference on Alzheimer's and Parkinson's Diseases (ADPD)

    On the 26-31st March, the 14th International Conference on Alzheimer's and Parkinson's Diseases (ADPD) and related neurological disorders was held in Lisbon, Portugal. This year, almost the entire team 1 and team 6 went to this major event and our students: Laurie Arnaud, Laura García González and Dominika Pilat took the opportunity to present their work on a poster.

  8. New publication from the NeuroCyto team in Nature Communications: Perform advanced microscopy experiments thanks to NanoJ-Fluidics

    The LEGO Pumpy (or more officially NanoJ-Fluidics) paper is out in Nature Communications! A joint venture between the INP NeuroCyto team and the Henriques lab, this article (previously available as a preprint on bioRxiv) details how to build a fully open-source multi-channel syringe pumps with LEGO and Arduino.

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INP in numbers

  • 126 members
  • 44 researchers
  • 48 research assistants
  • 12 post-docs
  • 11 PhD

 

PRA - Plan de Reprise des Activités - INP / VECT-Horus

Après près de 2 mois de fermeture du laboratoire, un plan de reprise des activité vient d'être mis en place pour une sortie de confinement progressive et évolutive en toute sécurité. La reprise de nos activités au laboratoire va se concrétiser à partir du 12/05 mais seulement de manière partielle. Il s’agit d’une part de respecter les recommandations de nos tutelles, d’autre part de travailler dans les meilleures conditions possibles sur le plan de notre sécurité qui reste notre première priorité. 

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Réouverture du Campus Timone

CNRS - Amélioration de la Qualité de Vie au Travail

Le projet « 80 plantes pour les 80 ans du CNRS » avance : la liste des plantes à commander a été établie. Les commandes seront passées dès que les jardineries pourront vendre les plantes ornementales. En effet, l’Etat a autorisé, en avril, la réouverture des jardineries et pépinières, pour vendre des graines, bulbes, plantes aromatiques et plants à vocation alimentaire. Les plantes décoratives ne sont pas remises à la vente, pour de meilleures conditions sanitaires d’achat.

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l'INP se mobilise contre le COVID-19

Dans le cadre des actions de la lutte contre le COVID-19, conformement aux dispositions prises par Aix Marseille Université en concertation étroite avec le CNRS, CEA, INRAE, INRIA et INSERM, l'INP comme la plupart des laboratoires de recherche a fait don d'une grande partie de ses kits et consommables pouvant servir à prévenir, dépister et soigner dans le cadre de la lutte contre le COVID-19. Un grand merci à toutes celles et tous ceux qui ont participé au recensement et à la collecte de ces masques, gants, reactifs, etc ...

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The GlioME team published a new article in Oncotarget journal: EB1-dependent long survival of glioblastoma-grafted mice with the oral tubulin-binder BAL101553 is associated with inhibition of tumor angiogenesis.

Our study shows that a treatment with the microtubule-destabilizing agent BAL101553 counteracts tumor angiogenesis by acting on glioblastoma stem-like cells, in an EB1-dependent manner. This work provides new insights into the therapeutic targeting of cancer stem-like cells.

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Aurélie Tchoghandjian, jeune chercheur dans l'équipe GlioME a brillament obtenu son Habilitation à Diriger les Recherches (HDR)

Aurélie Tchoghandjian a soutenu son Habilitation à Diriger les Recherches (HDR) devant un jury d'experts composé de cliniciens : Pr. Nicolas André, Pr. François Ducray, Pr. Dominique Figarella-Branger; et de chercheurs : Dr. Emmanuelle Huillard et Dr. Monique Dontenwill.

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