The Institute of NeuroPhysiopathology (INP) is a training and research centre of excellence that combines basic and translational research to study neural cell organisation, function and interaction, the molecular and cellular bases of major brain diseases, and to develop innovative cellular and molecular therapeutic strategies.
The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.
A look back at a day spent with the Petra NetWork
A moment of science with research players: PhD students, engineers and researchers, as well as representatives of the ARTC Sud and Fondation Flavien associations, which support neuro-oncology research.
INP platform PINT together with AFMB and IMM are glad to announce their third inter-platform interactome workshop entitled "Methods to study Molecular Interactions" MEDIM 2024, that will take place from monday April 15th to friday 19th 2024.
Looking to confirm the interaction between a drug and its target?
Wanting to characterize the interaction between a receptor and its ligand?
Pour fêter dignement la fin de cette année 2023 riche en nouveautés, publications, créations d'équipes, brevets, financements, ... l'équipe animation de l'INP a organisé la première édition du concours de la plus belle porte de Noël. Les 11 équipes de l'INP et de celles de Vect-Horus se sont regroupées par ailes et ont joué le jeu à fond et espèrent que cette initiative fera boule de neige au sein de la Faculté des Sciences Médicales et Paramédicales pour 2024 ...
Nicolas Pascariello and the Bouches-du-Rhône department came to shoot a short video to explain what we are doing in the lab! You can watch the video here
🎉 Congratulations to Rayane Hedna, who brilliantly defended her thesis "Apports thérapeutiques des thiazoloflavonoïdes ciblant Tau dans les glioblastomes" and was awarded the title of Docteur of Aix-Marseille University on the 30th of november. The jury composed of Isabelle Arnal, Cyrille Garnier, Céline Gongora (president), Sophie Thiétot-Laurent, and her co-supervisors Gilles Breuzard and Hervé Kovacic.
The first Journal Club Alzheimer of the INP was a big success! Thanks again to Theresa and Christopher for their great talk.
See you in 2 weeks (21/12/2023) when Simone will discuss this BioRxiv paper (https://www.biorxiv.org/content/10.1101/37577527).
🎉 Congratulations to Victoria Hein, who brilliantly defended her thesis and was awarded the title of Docteur en biologie-santé, spécialité oncologie d'Aix-Marseille Université, with the congratulations of the jury.
On Tuesday November 28th, we welcomed a delegation from the Lviv City Council 🇺🇦 together with Aurélie Philippe and Vincent Audibert of the regional delegation of CNRS, Stephan Enoch for Aix Marseille Unversity and Sylvain Crespel for Aix-Marseille-Provence Métropole . The Lviv City Council, who were present in Marseille for the European Capital of Innovation Awards 2023 ceremony (they reached the 2nd runner up position) came to visit INP Nikon Center of Excellence for Neuro-NanoImaging.
The first Journal Club Alzheimer of the INP was a big success! Thanks again to Theresa and Christopher for their great talk.
See you in 2 weeks (21/12/2023) when Simone will discuss this BioRxiv paper (https://www.biorxiv.org/content/10.1101/37577527).
🎉 Congratulations to Victoria Hein, who brilliantly defended her thesis and was awarded the title of Docteur en biologie-santé, spécialité oncologie d'Aix-Marseille Université, with the congratulations of the jury.
On Tuesday November 28th, we welcomed a delegation from the Lviv City Council 🇺🇦 together with Aurélie Philippe and Vincent Audibert of the regional delegation of CNRS, Stephan Enoch for Aix Marseille Unversity and Sylvain Crespel for Aix-Marseille-Provence Métropole .
L'INP a participé au 7èmes journées scientifiques francophones du CALM qui étaient organisées par le Le Club Alzheimer de Montpellier les mardi 14 et mercredi 15 Novembre 2023, en distanciel et en présentiel. Au cours de ces 2 journées qui ont pour objectif de de dynamiser les échanges entre les chercheurs et cliniciens travaillant sur la maladie d'Alzheimer, Maud GRATUZE (équipe 2') a donné une conférence intitulée "Les macrophages de la bordure parenchymateuse : des cellules immunitaires qui régulent la pathologie tau et la neurodégénérescence associée" dans
The latest collaboration from the NeuroCyto team was just published in the Journal of Cell Science, and asks a simple question: how do microtubule and actin fight or cooperate with each other? The CytoMorpho lab of Manuel Théry and Laurent Blanchoin in Paris and Grenoble used complex in-vitro reconstitution to show how dense actin networks can stop microtubule growth.
Super-resolution microscopy is super-nice, but it can also be super-expensive or super-complicated. But now it's super-simple to get nanoscale details of your favorite cells with any kind of microscope, thanks to the enhanced version of the SRRF algorithm just published in Nature Methods!
🎉 Congratulations to Emmanuel Snacel-Fazy, who brilliantly defended his thesis and was awarded the title of Docteur en biologie-santé, spécialité oncologie d'Aix-Marseille Université, with the congratulations of the jury.
Emmanuel is now an ATER in the GlioME team and is continuing the technological development of light-sheet imaging associated with the clearing technique he developed.
The NeuroCyto team published their latest work in the Journal of Cell Biology (article is available here), where they reveal the presence of distinct actin nanostructures within presynapses. The article is featured in the October issue of the journal, and made it to the cover that shows a nice picture of a neuron endogenously tagged for actin using CRISPR/Cas9.
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