The Institute of NeuroPhysiopathology (INP) is a training and research centre of excellence that combines basic and translational research to study neural cell organisation, function and interaction, the molecular and cellular bases of major brain diseases, and to develop innovative cellular and molecular therapeutic strategies.
The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.
The INP is proud to announce that, this year, four of its members have had their projects successfully granted by the French National Research agency (ANR - generic call 2021): Pascale Barbier (team 9), Christophe Leterrier (team 7), Emmanuel Nivet (team 6) and Aurélie Tchoghandjian (team 8).
La saison estivale est déjà amorcée, certains sont déjà en vacances (la chance !) et d'autres font de la résistance au labo. Le comité des fêtes de l'INP en a profité pour réunir les présents autour d'un pique-nique, juste avant le déménagement de l'équipe 8 !
Joyeuses vacances estivales à tous. Que nous revenions tous reposés, motivés et pleins d'ambitions et d'idées pour de belles recherches scientifiques à accomplir à la rentrée :-)
The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS), is the sixth version of the international standard for the classification of brain and spinal cord tumors. Building on the 2016 updated fourth edition and the work of the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW), the 2021 fifth edition introduces major changes that advance the role of molecular diagnostics in CNS tumor classification.
Vect-Horus and RadioMedix are pleased to announce the FDA clearance of exploratory Investigational New Drug (eIND) application to evaluate 68Ga-RMX-VH for the detection and mapping of Low Density Lipoprotein Receptor (LDLR) overexpressed in Glioblastoma Multiforme (GBM).
To learn more visit the article in the BUSINESS WIRE site
Last week the 8th annual seminar of Canceropole PACA took place in the Palais des Congrés of Saint Raphaël. During these 2 days a great number of scientific presentations were given, including different aspects of INP research coming from team 8, team 9 and the platform PINT, during the poster sessions.
La semaine dernière, vendredi 18 juin 2021, nous avons reçu la visite du Président de l’Université Eric Berton. Il était accompagné par la nouvelle Directrice Générale des Services de AMU Laurence Corvellec, le Doyen de la Faculté des Sciences Médicales et Paramédicales Georges Leonetti et l'assesseur à la Recherche la FSMP Jean Louis Mège.
Each week-end the local newspaper La Marseillaise puts the spotligh on a scientific topic and on a team of research in a scientific page called "Provence Terre de Science". After the page about Alzheimer disease last year (see here), INP research has been highligthed with the interview of Jean Marc Sabatier (Cytoskeleton and Neurophysiopathology team) for his work on venoms, and then Christophe Letterier (NeuroCyto team) for his work on superresolution imaging of neurons, in La Marseillaise week-end editions of may 22nd-24th and
The NeuroCyto team has two new articles just out in Nature Communications! Click for more details >>
Chiara Bastiancich, Post-doc in the GlioME team presented her ongoing GlioRET project at the European Symposium on Controlled Drug Delivery.
Her poster "Elucidating the tumor resection microenvironment of glioblastoma toward the development of fit-for-purpose local treatments" won over the cogress jury !
Emmanuel Snacel-Fazy, a 2nd year doctoral student in the GlioME team, won the best poster award at yesterday's "Conference Annuelle de L'institut Cancer et Immunologie (ICI)", Thursday 31 March 2022.
His work on the "Remodelling of the glioblastoma immune landscape by smac mimetic GDC-0152" has been appreciated and rewarded. Once again, congratulations!
Dr Romain Appay, pathologist at the Timone Hospital and PhD student in the GioME team, has published a new research paper entitled "Rosette-forming glioneuronal tumours are midline, FGFR1- mutated tumours" in the Neuropathology and Applied Neurobiology journal.
The latest article for NPD team 1 has been published this month into the Journal of Neuroinflammation.
Membrane-type matrix metalloproteinase 5 (MT5-MMP) deficiency in the 5xFAD mouse model of Alzheimer's disease reduces brain neuroinflammation along with amyloidosis, and prevents deficits in synaptic activity and cognition in prodromal stages of the disease. In addition, MT5-MMP deficiency prevents interleukin-1 beta (IL-1β)-mediated inflammation in the peripheral nervous system.
Don't miss the next Neuro'binar of NeuroMarseille with Emmanuel Nivet (Team 6) !
Next Tuesday, on March 22nd, 2022, at 1 pm online, discover Dr Emmanuel Nivet's work in the 13th edition of Neuro'binar:
🔘 Emmanuel Nivet (INP) will present his research topic entitled: "Human induced pluripotent stem cells to study the role of astrocytes in Alzheimer’s disease"
If you want to know more about the treatment of glioblastoma with Gold Nanorods, click on the title "Well-Defined Polyethylene Glycol Microscale Hydrogel Blocks Containing Gold Nanorods for Dual Photothermal and Chemotherapeutic Therapy" , a publication co-authored by Chiara Bastiancich, post-doc in the GlioME team.
Application Deadline : 30 September 2023
General information
Reference : UMR7051-MAUGRA-001
Number of position : 1
Workplace : MARSEILLE 05
Type of Contract : FTC Scientist
Contract Period : 24 months
Expected date of employment : 1 January 2024
Proportion of work : Full time
Remuneration : Between €2,932 and €4,669 gross per month depending on experience.
Desired level of education : Niveau 8 - (Doctorat)
Experience required : Indifferent
To nicely end 2021 year, Dominika Pilat, student in Neural Plasticity and Degeneration Team (Team 1), successfully defended her thesis on the 16th of December. She gave a very clear, precise and comprehensive presentation highlighting the pivotal role of MT5-MMP in the neuroinflammation in an Alzheimer’s Disease model.
Participating in the virtual conference "Tumor Microenvironment Heterogeneity in Cancer Progression: Challenge or Opportunity", Emmanuel Snacel-Fazy, a 2nd year PhD student in the GlioME team won the prize for the best presentation on the "Remodeling of the glioblstoma immune landscape by smac mimetic GDC-0152".
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