NeuroTimone Facility (PFNT)

The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.

News

  1. De "nouvelles têtes" dans l'équipe GlioME !

    L'équipe GlioME a le plaisir d'accueillir actuellement 3 nouveaux étudiants (de gauche à droite sur la photo):

    - Victoria Hein, doctorante en 1ère année, qui débute sa thèse sur le thème "Cellules souches de glioblastome et gangliosides : vers de nouvelles approches thérapeutiques", co-encadrée par Emeline Tabouret et Dominique Figarella-Branger.

  2. Christophe Leterrier (NeuroCyto team) in Nature Materials

    Christophe Leterrier from the NeuroCyto team just published a study in collaboration with the Cytomorpho lab  - Manuel Théry & Laurent Blanchoin, CEA Paris/Grenoble. Entitled “Self-repair protects microtubules from destruction by molecular motors”, this work demonstrates how motor proteins kinesins and dynein can damage microtubule while walking on them, triggering repair by incorporation of new tubulin monomers inside the microtubule lattice. It was published on Jan.

  3. Dominika Pilat (Team 1) on the Neurobinar #4 (NeuroMarseille) !

    Dominika Pilat will be presenting on the Neurobinar #4 on January 21 at 4 pm on Zoom.

    For this fourth edition, NeuroMarseille is pleased to welcome Cédric Maurange (IBDM), Dominika Pilat (INP) and Borloz Émilie (MMG). Dominika Pilat and Borloz Émilie will introduce their respective theses in a cross presentation. After a question session, Cédric Maurange (IBDM) will explain his research on genetic programmes modifying the properties of neural stem cells during development.

  4. INP goes green !

    When you say New Year, you say new resolutions! 
    Increasingly present at the heart of debates and minds, ecology is part of our daily lives and it is our duty to do everything we can to reduce our ecological footprint. The INP has decided to be mobilized for ecology, at its own level. 

    To begin with, we have set up a plastic bottle collection system to recycle our bottles in a short circuit. This is done via the collection system proposed by the company Yoyo, which guarantees delivery to the nearest recycling plant for 100% recycling! We have three collection points on our premises (salle de convivialité R+3, R+1 et R+2 vert). 

  5. Christophe Leterrier (NeuroCyto team) in the Journal of Neuroscience: “A Pictorial History of the Neuronal Cytoskeleton”

    Christophe Leterrier, leader of the NeuroCyto team, just published a special review for the 40th anniversary issue of the Journal of Neuroscience. Entitled “A Pictorial History of the Neuronal Cytoskeleton”, it is a journey through the history of the neuronal cytoskeleton in pictures.

  6. Fondation Vaincre Alzheimer's visit at the Institute of Neurophysiopathology (INP)

    A few weeks ago, the Vaincre Alzheimer Foundation came to visit the Institute of NeuroPhysiopathology and made a short documentary on the team Neural Plasticity and Degeneration (Team 1), led by Santiago Rivera who was recently funded by the Foundation. It was an opportunity for him to thank Vaincre Alzheimer and the donors and talk about the importance of MT5-MMP, a protease that contributes to the pathophysiological mechanisms of Alzheimer’s disease and may become a potential new target.

  7. MedIM 2020 : retour d'expérience

    Dans la semaine du lundi 07 décembre au vendredi 11 décembre s'est tenue avec succès la première édition de l'atelier MedIM (Methodes d'étude des Interactions Moléculaires) co-organisé par la Plateforme INteractome Timone (PINT) de l’INP, la plateforme de Biologie Structurale de l’AFMB et les plateformes de l’IMM, toutes trois labellisées "Plateformes Technologiques du site d'Aix-Marseille".

  8. New publication in Frontiers in Oncology

Pages

INP in numbers

  • 126 members
  • 44 researchers
  • 48 research assistants
  • 12 post-docs
  • 11 PhD

 

Zoom sur la 5ème édition de la classification de l'OMS des tumeurs du Système Nerveux Central

Membre expert du comité éditorial et co-auteur de plusieurs chapitres de la 5ème édition de la Classification des tumeurs du SNC de l’OMS parue le 12 novembre dernier, Dominique Figarella-Branger (Equipe 8 GlioME) a dirigé la rédaction d'un article de revue en français sur cette nouvelle classification, récemment publié dans les Annales de Pathologie: https://authors.elsevier.com/c/1eB1VtB1GOhjB

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Recent works on Zinc binding to S100A1 and to NCS-1 published in Biomolecules and in  International Journal of Molecular Sciences respectively

Team 9 (Cytoskeleton and Neurophysiopathology) and platform PINT (platform interactive Timone) are happy to see the almost simultaneous publications of two papers about about the impact of Zn2+ binding to NCS1 and to S100A1 respectively with their collaborators from Belozersky Institute of Physico Chemical Biology, Lomonosov Moscow State University, while the third one about Tau protein Zn2+ binding sites has been under review for already 3 months ... 

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INP participation to AMU's 1st Digital Sciences and AI for Health conference

On November 25 and 26, the conference "Digital Sciences and Artificial Intelligence for Health at Aix-Marseille University" was held in the Grisoli amphitheater & the Great Hall of the Faculty of Medical and Paramedical Sciences - Timone. 

The aim of this conference was to formally bring together for the first time all the actors of Aix-Marseille University and the University Hospital Center involved in the digital and AI/health field, whether they are clinicians or theoreticians. 

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L'institut TranceScience, présidé par François Féron, dans Le Monde

Plusieurs chercheurs de la communauté marseillaise des neurosciences, notamment l’équipe d’Agnès Trébuchon, mènent des recherches sur les fondamentaux et les effets thérapeutiques de la transe cognitive auto-induite. Tout comme l’hypnose ou la méditation, il s’agit d’un état modifié de conscience, induit par la seule volonté de chacun.

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New Post-doctoral fellow in team 1

Neural Plasticity and Degeneration team has recently welcomed Shweta SONAWANE.

Shweta is from Mumbai (India) she did her Ph.D. at the Biochemical sciences division of CSIR - National Chemical Laboratory in Pune (India).

Her doctoral research was largely focused on Tau pathology in Alzheimer’s disease studying in particular the effect of glycated and phosphorylated Tau on cytoskeleton integrity as well as aggregation propensity in order to find small molecules that could attenuate Tau aggregation and prevent its glycation.

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Just out: NeuroCyto team in Science

The NeuroCyto team has a new publication out! Published on November 5th in Science, this article elucidates how adenosine A2A receptors drive removal of inhibitory synapses depending on their activity. This is a fruitful collaboration with the labs of Sabine Lévi at Institut du Fer à Moulin (IFM) in Paris and Christophe Bernard at Institut de Neuroscience des Systèmes (INS) in Marseille.

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