NIVET Emmanuel
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Publications
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Mutations in specific domains of MT5-MMP prevent the accumulation of toxic APP metabolites and serve as templates for peptide-based therapeutics in human in vitro models of Alzheimer's disease2024
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High and low permeability of human pluripotent stem cell–derived blood–brain barrier models depend on epithelial or endothelial featuresFASEB Journal2023
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High and low permeability of human pluripotent stem cell-derived Blood Brain barrier models depend on epithelial or endothelial features2022
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The Alzheimer’s disease risk factor APOE4 drives pro-inflammation in human astrocytes via HDAC-dependent repression of TAGLN32022
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The C-terminal of MT5-MMP regulates C99 processing and Aβ levels in a cell model of Alzheimer's disease2022
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APOE4 primes inflammation in human astrocytes through the downregulation of a newly discovered target candidatevv2021
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APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-κB activationCell Reports2022
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APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-κB activationCell Reports2022
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The Alzheimer’s disease risk factor APOE4 drives pro-inflammation in human astrocytes via HDAC-dependent repression of TAGLN32021
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MT5-MMP is a modulator of inflammation: a study in murine and human neural cells related to Alzheimer’s disease2021
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Human iPSCs-derived astrocytes reveal APOE as a critical modulator of inflammation that could underlie Alzheimer’s disease pathogenesis2021
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Deficiency in MT5-MMP Supports Branching of Human iPSCs-Derived Neurons and Reduces Expression of GLAST/S100 in iPSCs-Derived AstrocytesCells2021
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MT5-MMP controls APP and β-CTF/C99 metabolism through proteolytic-dependent and -independent mechanisms relevant for Alzheimer’s disease2020
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Impaired expression of the COSMOC/MOCOS gene unit in ASD patient stem cellsMolecular Psychiatry2020
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Pharmacological Transdifferentiation of Human Nasal Olfactory Stem Cells into Dopaminergic NeuronsStem Cells International2019
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Enriched Differentiation of Human Otic Sensory Progenitor Cells Derived From Induced Pluripotent Stem CellsFrontiers in Molecular Neuroscience2018
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Modeling human early otic sensory cell development with induced pluripotent stem cellsPLoS ONE2018
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From Blood to Lesioned Brain: An In Vitro Study on Migration Mechanisms of Human Nasal Olfactory Stem CellsStem Cells International2017
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Modifiers of Neural Stem Cells and Aging: Pulling the Trigger of a Neurogenic DeclineCurrent Stem Cell Reports2016
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Establishment of human iPSC-based models for the study and targeting of glioma initiating cellsNature Communications2016
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Identification of novel long noncoding RNAs underlying vertebrate cardiovascular developmentCirculation2015
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In vivo activation of a conserved microRNA program induces mammalian heart regenerationCell Stem Cell2014
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The generation of kidney organoids by differentiation of human pluripotent cells to ureteric bud progenitor-like cellsNature Protocols2014
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Conversion of human fibroblasts into monocyte-like progenitor cellsStem cells (Dayton, Ohio)2014
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Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cellsNature Cell Biology2013
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Reprogramming of human fibroblasts to pluripotency with lineage specifiersCell Stem Cell2013
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[Resetting Parkinson's disease patient-derived cells to unveil new pathological marks]Médecine/Sciences2013
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Conversion of pericytes to neurons: a new guest at the reprogramming conventionStem Cell Research and Therapy2013
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Conversion of human fibroblasts to angioblast-like progenitor cellsNature Methods2013
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Progressive degeneration of human neural stem cells caused by pathogenic LRRK2Nature2012
