The Institute of NeuroPhysiopathology (INP) is a training and research centre of excellence that combines basic and translational research to study neural cell organisation, function and interaction, the molecular and cellular bases of major brain diseases, and to develop innovative cellular and molecular therapeutic strategies.
The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.
On February 22nd at 1 pm don't miss the next Neurobinar of NeuroMarseille ! You will get a chance to meet Adam Williamson, principal investigator at the INS, Gaelle Alhaddad, 2nd year PhD student at the LNC and Pedro Belio Mairal, 3rd year student in the "Neural Plasticity and Degeneration" team of INP. Gaelle and Pedro will each present the other's thesis topic and Adam will explain his work on "Non-invasive deep brain stimulation in Epilepsy using Temporal Interference".
Within the cycle M&M’s – Muscle Monday Seminars of the Institute’s Myology Centre for Research, on January 17 Michel Khrestchatisky (CNRS Research Director, Director of the Institute for Neurophysiopathology) Co-Founder & Scientific Counsel of Vect-Horus presented the conference entitled “"Development of molecular vectors for targeted delivery of RNAi via receptor-mediated transport".
Vect-Horus annonce l’accord de la Région SUD Provence-Alpes-Côte d’Azur, responsable de la mise en œuvre du dispositif REACT-EU dans le cadre du Programme Opérationnel FEDER-FSE, pour une subvention de plus d’un million d’euros. Ce projet est financé avec le concours de l’Union européenne avec le Fonds Européen de Développement Régional.
Pour plus d' information, lisez l'article complet dans BUSINESS WIRE.
We are please to welcome Guillaume Benhora-Chabeaux for his 5-month Master internship (2nd year) in the Nivet team. After obtaining a first Master degree in Cognitive Science (MASCO) from the Aix-Marseille University, with the highest honours, Guillaume has enrolled the Master in Neuroscience (cellular and molecular neuroscience). Guillaume will be working on the crosstalk between inflammation and a susceptibility to neurodegeneration using in vitro and in vivo models.
Dr Emmanuel Nivet has been appointed as a new member of the European Scientific Advisory Board (SAB) of a joint organization unifying the Alzheimer Forschung Initiative e.V. (AFI), Germany, Alzheimer Nederland (AN), The Netherlands and Fondation Vaincre Alzheimer (FVA), France. Each of the above organizations is dedicated to funding dementia research in its own country.
Membre expert du comité éditorial et co-auteur de plusieurs chapitres de la 5ème édition de la Classification des tumeurs du SNC de l’OMS parue le 12 novembre dernier, Dominique Figarella-Branger (Equipe 8 GlioME) a dirigé la rédaction d'un article de revue en français sur cette nouvelle classification, récemment publié dans les Annales de Pathologie: https://authors.elsevier.com/c/1eB1VtB1GOhjB
Un article de référence, facile d'accès, pour toute personne souhaitant être à la page sur la classification des tumeurs du SNC!
Team 9 (Cytoskeleton and Neurophysiopathology) and platform PINT (platform interactive Timone) are happy to see the almost simultaneous publications of two papers about about the impact of Zn2+ binding to NCS1 and to S100A1 respectively with their collaborators from Belozersky Institute of Physico Chemical Biology, Lomonosov Moscow State University, while the third one about Tau protein Zn2+ binding sites has been under review for already 3 months ...
In collaboration with other teams, the glioME team participated in two new scientific publications:
"Deciphering the heterogeneity of the Lyve1+ perivascular macrophages in the mouse brain": https://www.nature.com/articles/s41467-022-35166-9
"Challenges in glioblastoma research: focus on the tumor microenvironment": https://pubmed.ncbi.nlm.nih.gov/36400694/
Our team is pleased to welcome Mensah Loko for a 6 months Master internship (from November 2022) in Integrative Biology and Physiology: Integrative approach to the functions of life: from gene to pathology. The subject of his internship is the role of Adrenomedullin expressed by glioblastoma-associated endothelial cells in promoting a stable and functional angiogenesis.
We are happy to celebrate the release of 3 first author papers on Myotoxin-3 from a snake venom as a new microtubule targeting agent, on the mechanism of action of Zinc induced aggregation of tau, and a review article on tau as a therapeutic target for cancer, for team 9 three PhD students : Cecilia, Dahbia and Rayane, this month :
Clara Camilla, PhD student, Biology-Health - Oncology speciality, is starting her thesis on the theme: "Evaluation of Longitudinal Genomic Alterations in Diffuse Low Grade Gliomas in Adults".
Emeline Tabouret and Aurélie Tchoghandjian, in collaboration with Thierry Virolle's team at the l'Institut de Biologie Valrose in Nice, are among the two winners to have obtained "Action structurante" funding from the Cancéropôle PACA.
This funding aims to structure the neuro-oncology at the preclinical and translational level in the region (between Marseille and Nice) and will be used to create the PETRA (PrEclinical and TRAnslational Research) platform on these two sites.
Chiara Bastiancich published the last article of her first postdoc on GRAVITY project 🎉
The challenging goal was: delivering to the brain metallic nanoparticles via focused ultrasound-mediated blood-brain barrier (BBB) permeabilization, to heat them using lasers for glioblastoma photothermal therapy! In this paper she shows one of the steps to reach this daunting task.
Aix Marseille Université | All rights reserved - Legal notice
