The latest article for NPD team 1 has been published this month into the Journal of Neuroinflammation.

Membrane-type matrix metalloproteinase 5 (MT5-MMP) deficiency in the 5xFAD mouse model of Alzheimer's disease reduces brain neuroinflammation along with amyloidosis, and prevents deficits in synaptic activity and cognition in prodromal stages of the disease. In addition, MT5-MMP deficiency prevents interleukin-1 beta (IL-1β)-mediated inflammation in the peripheral nervous system.

Don't miss the next Neuro'binar of NeuroMarseille with Emmanuel Nivet (Team 6) !

Next Tuesday, on March 22nd, 2022, at 1 pm online, discover Dr Emmanuel Nivet's work in the 13th edition of Neuro'binar:

🔘  Emmanuel Nivet (INP) will present his research topic entitled: "Human induced pluripotent stem cells to study the role of astrocytes in Alzheimer’s disease"

🔘  Hannah Ihme (INT) and Martha Montse Rangel-Sosa (IBDM) - Ph.D. students - will present each other's Ph.D. projects in 5 min.

To nicely end 2021 year, Dominika Pilat, student in Neural Plasticity and Degeneration Team (Team 1), successfully defended her thesis on the 16th of December. She gave a very clear, precise and comprehensive presentation highlighting the pivotal role of MT5-MMP in the neuroinflammation in an Alzheimer’s Disease model. The jury was unanimous to underline the great work Dominika accomplished during the four years she has spent at the INP leading to the publication of an article into the Journal of Neuroinflammation in which she is first author.

Participating in the virtual conference "Tumor Microenvironment Heterogeneity in Cancer Progression: Challenge or Opportunity", Emmanuel Snacel-Fazy, a 2nd year PhD student in the GlioME team won the prize for the best presentation on the "Remodeling of the glioblstoma immune landscape by smac mimetic GDC-0152".

Within the cycle M&M’s – Muscle Monday Seminars of the Institute’s Myology Centre for Research, on January 17 Michel Khrestchatisky (CNRS Research Director, Director of the Institute for Neurophysiopathology) Co-Founder & Scientific Counsel of Vect-Horus presented the conference entitled “"Development of molecular vectors for targeted delivery of RNAi via receptor-mediated transport".