GRATUZE Maud
Onglets principaux
Publications
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Age-dependent impact of streptozotocin on metabolic endpoints and Alzheimer's disease pathologies in 3xTg-AD miceNeurobiology of Disease2024
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Parenchymal border macrophages regulate tau pathology and tau-mediated neurodegenerationLife Science Alliance2023
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Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in miceScience Translational Medicine2023
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Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathyMolecular Neurodegeneration2023
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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4Neuron2023
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APOE Antibody Inhibits Aβ‐Associated Tau Seeding and Spreading in a Mouse ModelAnnals of Neurology2022
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Activated microglia mitigate Aβ-associated tau seeding and spreadingJournal of Experimental Medicine2021
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Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microgliaNeuron2021
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Targeting pre-synaptic tau accumulation: a new strategy to counteract tau-mediated synaptic loss and memory deficitsNeuron2021
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APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular functionScience Translational Medicine2021
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Impact of TREM2R47H variant on tau pathology–induced gliosis and neurodegenerationJournal of Clinical Investigation2020
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SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain InjuryNeuron2020
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Circadian and sleep/wake-dependent variations in tau phosphorylation are driven by temperatureSleep2020
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TREM2 function impedes tau seeding in neuritic plaquesNature Neuroscience2019
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Arterial Stiffness Due to Carotid Calcification Disrupts Cerebral Blood Flow Regulation and Leads to Cognitive DeficitsJournal of the American Heart Association2019
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The toxin MPTP generates similar cognitive and locomotor deficits in hTau and tau knock-out miceBrain Research2019
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Administration of the benzodiazepine midazolam increases tau phosphorylation in the mouse brainNeurobiology of Aging2019
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Tau, Diabetes and Insulin2019
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New insights into the role of TREM2 in Alzheimer’s diseaseMolecular Neurodegeneration2018
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Relation mutuelle entre Tau et signalisation centrale de l’insulineMédecine/Sciences2018
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[Brain insulin signaling and Tau: impact for Alzheimer's disease and Tauopathies]Médecine/Sciences2018
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Mutual relationship between Tau and central insulin signalling: consequences for AD and Tauopathies ?Neuroendocrinology2018
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Differential effects of voluntary treadmill exercise and caloric restriction on tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology fed with Western dietProgress in Neuro-Psychopharmacology and Biological Psychiatry2017
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Regulation of brain insulin signaling: A new function for tauJournal of Experimental Medicine2017
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Insulin deprivation induces PP2A inhibition and tau hyperphosphorylation in hTau mice, a model of Alzheimer’s disease-like tau pathologyScientific Reports2017
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Tau hyperphosphorylation in the brain of ob/ob mice is due to hypothermia: Importance of thermoregulation in linking diabetes and Alzheimer's diseaseNeurobiology of Disease2017
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Characterization of l -Theanine Excitatory Actions on Hippocampal Neurons: Toward the Generation of Novel N -Methyl- d -aspartate Receptor Modulators Based on Its BackboneACS Chemical Neuroscience2017
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High-fat, high-sugar, and high-cholesterol consumption does not impact tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathologyNeurobiology of Aging2016
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Hypothermia mediates age-dependent increase of tau phosphorylation in db/db miceNeurobiology of Disease2016
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Is Huntington's disease a tauopathy?Brain - A Journal of Neurology2016
