APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function

authors

  • Xiong Monica
  • Jiang Hong
  • Serrano Javier Remolina
  • Gonzales Ernesto
  • Wang Chao
  • Gratuze Maud
  • Hoyle Rosa
  • Bien-Ly Nga
  • Silverman Adam
  • Sullivan Patrick
  • Watts Ryan
  • Ulrich Jason
  • Zipfel Gregory
  • Holtzman David

abstract

Targeting APOE using an anti-APOE antibody ameliorates amyloid pathology while protecting cerebrovascular integrity and function.

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