The Institute of NeuroPhysiopathology (INP) is a training and research centre of excellence that combines basic and translational research to study neural cell organisation, function and interaction, the molecular and cellular bases of major brain diseases, and to develop innovative cellular and molecular therapeutic strategies.
The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.
On december 10th 2022, PINT INP and Vect-Horus members met in the Hippodrome Borély for the "Course des Lumières" organized by Foundation Recherche Alzheimer. It was freezing but together with 600 or something others, they walked 5 km or ran 8 km, to light up the night against Alzheimer's disease and for all patients, carrying a luminous object. See a few pictures below
Simple Summary
The Cancéropole PACA has created a web page for the PETRA platform with all the necessary information and the contact form: PETRA web page.
In collaboration with other teams, the glioME team participated in two new scientific publications:
"Deciphering the heterogeneity of the Lyve1+ perivascular macrophages in the mouse brain": https://www.nature.com/articles/s41467-022-35166-9
"Challenges in glioblastoma research: focus on the tumor microenvironment": https://pubmed.ncbi.nlm.nih.gov/36400694/
Our team is pleased to welcome Mensah Loko for a 6 months Master internship (from November 2022) in Integrative Biology and Physiology: Integrative approach to the functions of life: from gene to pathology. The subject of his internship is the role of Adrenomedullin expressed by glioblastoma-associated endothelial cells in promoting a stable and functional angiogenesis.
We are happy to celebrate the release of 3 first author papers on Myotoxin-3 from a snake venom as a new microtubule targeting agent, on the mechanism of action of Zinc induced aggregation of tau, and a review article on tau as a therapeutic target for cancer, for team 9 three PhD students : Cecilia, Dahbia and Rayane, this month :
Clara Camilla, PhD student, Biology-Health - Oncology speciality, is starting her thesis on the theme: "Evaluation of Longitudinal Genomic Alterations in Diffuse Low Grade Gliomas in Adults".
Emeline Tabouret and Aurélie Tchoghandjian, in collaboration with Thierry Virolle's team at the l'Institut de Biologie Valrose in Nice, are among the two winners to have obtained "Action structurante" funding from the Cancéropôle PACA.
This funding aims to structure the neuro-oncology at the preclinical and translational level in the region (between Marseille and Nice) and will be used to create the PETRA (PrEclinical and TRAnslational Research) platform on these two sites.
Join us on Tuesday 27 June 2023 from 1pm to 2pm for the 6th episode of the Canceropôle's "Seminar Series"!
Chiara will talk about her work on "A multidisciplinay journey of successes & pitfalls towards the development of tailored local treatments for glioblastoma"
==> ZOOM link
Assistée par Guillaume Thoraval, souffleur de l’université Paris cité, Nadia a elle-même créé des pièces en verre. Elle a été accueillie par le Fab-Lab de Paris Sorbonne, au labo de biologie pour la mise en culture et l’entretien des bactéries. L’œuvre présentée les 23 et 24 mai a reçu un franc succès et la qualité, ainsi que la démarche scientifique et artistique ont impressionnés les professionnels du milieu de l’art et les membres de l’institut de France, à laquelle est affiliée la fondation Laccolade.
Une exposition collective est prévue pour l’année prochaine.
Nathalie et Aurélie ont eu le plaisir d'accueillir dans l'équipe Lucas Gola, élève de première du Lycée Notre Dame de France dans le cadre du dispositif "Apprentis Chercheurs" porté par l'association "Arbre des connaissances".
INP Team 9 is pleased to announce the launch of the COST Action "Net4Brain: A comprehensive Network Against Brain Cancer". This initiative, led by Prof.
Le projet « Validation de nouveaux agents ciblant les microtubules et pouvant traverser la barrière hémato-encéphalique pour le traitement du glioblastome » déposé à l’appel « Repositionnement de molécules en prématuration » du Canceropôle Provence Alpes Côte d’Azur par Philipp Tsvetkov (plateforme PINT) a été retenu par le Comité Scientifique du Canceropole PACA pour être financé à hauteur de 30 000 euros. Sont impliquées dans ce projet les équipes 9 et 8 et leurs plateformes associées respectives
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