NeuroTimone Facility (PFNT)

The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.

NCIS / PImaNT

PINT

qPCR

SCeNT

News

  1. INP Team 9 participated in a joint review on Tau molecular structures

    Tue. Mar 05 2019

    INP Cytoskeleton and Neurophysiopathology team, together with several leading groups in tau biology, has participated in a joint review of the field that just came out in Acta Neuropathologica Communications. This review summarizes the recent breakthroughs in deciphering the molecular structures, both physiological and pathological, of the elusive protein tau. 

    Read online (open access) : https://link.springer.com/article/10.1186/s40478-019-0682-x

    Title : The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

  2. New article of the cytoskeleton and neurophysiopathology team

    Fri. Feb 01 2019

    The last work of team 9 "Tau regulates the microtubule-dependent migration of glioblastoma cells via Rho-ROCK signaling pathway" is now published in J. cell. Science. This work identifies for the first time the role and mechanisms implicating the tau protein in the invasion processes of glioblastomas, very aggressive brain tumors. This work highlights the role of the Tau protein as a common target between cancers and neurodegeneration.

  3. Hervé Kovacic elected president of the CNU section 85

    Thu. Jan 10 2019

    Professor of Biophysics and Biomathematics at the Faculty of Pharmacy of Marseille, Hervé Kovacic is elected for a six-year term. Section CNU 85 manages the qualifications, promotions and bonuses of teacher-researchers specializing in physicochemical sciences and applied engineering in health. Doctor Pascale Barbier, also from team 9 of INP has been nominated as a member of the same CNU section.
  4. Jean-Michel Paumier successfully defended his doctoral thesis

    Wed. Dec 05 2018

    Jean-Michel Paumier, former PhD student in Team 1 (Neural Plasticity and Degeneration), has successfuly defended his thesis on Wednesday the 05th of December 2018. After few hours of a nice presentation followed by many questions, the examining board congratulated Jean-Michel for his good work and granted him the diploma of doctor in Neuroscience.
  5. 3 PhD students of the INP participate in the Neuroschool PhD Days 2018

    Thu. Dec 06 2018

    On December 6 and 7, 2018, Neuroschool PhD Days took place. In this edition entitled "Through the looking glass: beyond our reality", second-year neuroscience PhD students  were invited to present their work.

    It is in this context that the 3 PhD students of the INP took part: Laurie Arnaud, Audrey Jacq and Dominika Pilat.
  6. Vect-Horus announces agreement with Johnson & Johnson innovation

    Tue. Dec 11 2018

    Vect-Horus announced today the signing of a research collaboration agreement with Janssen Pharmaceuticals, Inc. one of the Janssen Pharmaceutical Companies of Johnson & Johnson. The goal of this collaboration is to use Vect-Horus’ proprietary technology to transport various Janssen monoclonal antibodies to the brain for the treatment of neurodegenerative diseases. This deal was facilitated by Johnson & Johnson Innovation Limited.
  7. Santiago Rivera gave two conferences on Alzheimer's disease

    Tue. Nov 20 2018

    The first conference entitled “Alzheimer’s disease, fears and hopes” was given at the meeting of the management boards of the french Vaincre l’Alzheimer and the german Alzheimer Forschung Initiative foundations that was held on November 16th 2018 at the Novotel Hotel Marseille Vieux Port.

    The second conference, in the context of the Conferences Cycle of the Institute of Neurosciences of the University of Barcelona, was entitled “ Membrane type-matrix metalloproteinases are newcomers to the Alzheimer’s field ”  ans was held on November 20th at the School of Pharmacy of the University of Barcelona.
  8. New article from the Neural Degeneration and Plasticity team

    Sat. Nov 17 2018

    The latest work from the Neural Degeneration and Plasticity team, in collaboration with the BBB and neuroinflammation team of Michel Khrestchatisky: "The pro-amyloidogenic effects of Membrane-type 1-Matrix Metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP trafficking" is now published in the FASEB Journal (doi: 10.1096/fj.201801076R). Our data unveil new mechanistic insights supporting the pro-amyloidogenic role of MT1-MMP based on APP processing and trafficking, and reinforces the idea that MT1-MMP may become a new potential therapeutic target in Alzheimer’s disease. 

Pages

INP in numbers

  • 126 members
  • 44 researchers
  • 48 research assistants
  • 12 post-docs
  • 11 PhD

 

NeuroSchool: a School of Neuroscience for and by AMU students

On September 12, over 300 students, teachers, researchers, clinicians and entrepreneurs participated in the launch of NeuroSchool, the school that unifies and harmonizes the teachings of the third year of the bachelor's degree (Neuroscience path), the master's degree and the PhD program in neuroscience. Funded by the National Research Agency and the A*Midex Foundation, NeuroSchool will benefit from a funding of approximately 10 million euros (over 10 years).

Undefined

Michel Khrestchatisky and Grigorios Kyriatzis (Early Stage Researcher, ESR), both members of the ITN Marie Curie project ECMED participated in the ECMED EU-GliaPhD international conference organized in Malta

Michel Khrestchatisky gave a talk on the ongoing projects of his group and biotechnology partner Vect-Horus, also member of the ECMED consortium, while Grigorios Kyriatzis presented results of his ongoing PhD project.       

Undefined

François Devred gave one of the 38 selected talks in EUROTAU 2018

#EUROTAU 2018 - European scientists involved in Tau research met in Lille to exchange new ideas and hypotheses on physiological and pathological roles of tau proteins (26-27th April 2018). François Devred gave one of the 38 selected talks in which he presented a new reversible oligomerization of tau protein evidenced in INP team 9, which could have a protective physiological role and prevent pathological aggregation of tau in neurodegenerative diseases. Next edition of EuroTau will be in 2020.

Photo © Valérie Buée Scherrer

Undefined

The CNRS press office selected one of our pictures to illustrate a press release about the fresco "étonnant vivant"

In the corridor of the Montparnasse-Bienvenüe Station, the CNRS exhibits an amazing fresco of 134 metres long on the most surprising living discoveries of the last 15 years.  One of our pictures, featured on the fresco has been selected by the CNRS press office to illustrate a press release entitled "« Étonnant Vivant » : une nouvelle exposition à la station Montparnasse-Bienvenüe"

English

Partners

                            

Aix-Marseille Université      

Aix Marseille Université | All rights reserved - Legal notice