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OUAFIK L'houssine
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OUAFIK L'houssine
PU-PH
Responsable Equipe 10
Position actuelle:
Professeur des Université - Praticien Hospitalier
lhoucine.OUAFIK@univ-amu.fr
0491324447
Team
Angiogenesis and Tumor Microenvironment
Localisation
Faculté des Sciences Médicales et Paramédicales couloir vert 3ème étage
Publications
http://api.archives-ouvertes.fr/search/?fq=authIdHal_i:17794&fl=title_s,en_title_s,docid,label_s,en_label_s,authIdHal_s,halId_s,structId_i,uri_s,keyword_s,en_keyword_s,authLastNameFirstName_s,journalTitle_s,abstract_s,en_abstract_s,producedDate_tdate,producedDateY_i,language_s&sort=publicationDate_s+desc
Antiproliferative Effects of Naja anchietae and Naja senegalensis Venom Peptides on Glioblastoma Cell Lines
Boughanmi Yasmine
Berenguer-Daizé Caroline
Balzano Marielle
Mosrati Hend
Moulard Maxime
Mansuelle Pascal
Fourquet Patrick
Torre Franck
de Pomyers Harold
Gigmes Didier
Ouafik Lhoucine
Mabrouk Kamel
Toxins
2024
Extreme Gradient Boosting Tuned with Metaheuristic Algorithms for Predicting Myeloid NGS Onco-Somatic Variant Pathogenicity
Pellegrino Eric
Camilla Clara
Abbou Norman
Beaufils Nathalie
Pissier Christel
Gabert Jean
Nanni-Metellus Isabelle
Ouafik L'Houcine
Bioengineering
2023
Impact of Molecular Biology in Diagnosis, Prognosis, and Therapeutic Management of BCR::ABL1-Negative Myeloproliferative Neoplasm
Abbou Norman
Piazzola Pauline
Gabert Jean
Ernest Vincent
Arcani Robin
Couderc Anne-Laure
Tichadou Antoine
Roche Pauline
Farnault Laure
Colle Julien
Ouafik L'Houcine
Morange Pierre
Costello Régis
Venton Geoffroy
Cells
2023
Adrenomedullin Secreted by Melanoma Cells Promotes Melanoma Tumor Growth through Angiogenesis and Lymphangiogenesis
Benyahia Zohra
Gaudy-Marqueste Caroline
Berenguer-Daizé Caroline
Chabane Norhimane
Dussault Nadège
Cayol Mylène
Vellutini Christine
Djemli Amina
Nanni Isabelle
Beaufils Nathalie
Mabrouk Kamel
Grob Jean-Jacques
Ouafik L'Houcine
Cancers
2022
1693P Incidence of NTRK genes fusion in adult brain tumours: A prospective cohort of 140 patients with cerebral gliomas and brain metastases
Métellus P.
Camilla C.
Bialecki E.
Beaufils N.
Vellutini C.
Pellegrino E.
Tomasini P.
Nanni I.
Ouafik L'Houcine
Annals of Oncology
2022
1693P Incidence of NTRK genes fusion in adult brain tumours: A prospective cohort of 140 patients with cerebral gliomas and brain metastases
Metellus Philippe
Camilla Clara
Bialecki Emilie
Beaufils Nathalie
Vellutini Christine
Pellegrino Eric
Tomasini Pascale
Nanni Isabelle
Ouafik L'Houcine
2022
Deep Learning Architecture Optimization with Metaheuristic Algorithms for Predicting BRCA1/BRCA2 Pathogenicity NGS Analysis
Pellegrino Eric
Brunet Theo
Pissier Christel
Camilla Clara
Abbou Norman
Beaufils Nathalie
Nanni-Metellus Isabelle
Métellus Philippe
Ouafik L'Houcine
BioMedInformatics
2022
Machine learning random forest for predicting oncosomatic variant NGS analysis
Pellegrino Eric
Jacques Coralie
Beaufils Nathalie
Nanni Isabelle
Carlioz Antoine
Metellus Philippe
Ouafik L'Houcine
Scientific Reports
2021
Role of the Tyrosine Phosphatase SHP-2 in Mediating Adrenomedullin Proangiogenic Activity in Solid Tumors
Sigaud Romain
Dussault Nadège
Berenguer-Daize Caroline
Vellutini Christine
Benyahia Zohra
Cayol Mylène
Parat Fabrice
Mabrouk Kamel
Vázquez Ramiro
Riveiro Maria
Metellus Philippe
Ouafik L'Houcine
Frontiers in Oncology
2021
Molecular characterization of fast-growing melanomas
Gaudy-Marqueste Caroline
Macagno Nicolas
Loundou Anderson
Pellegrino Eric
Ouafik L'Houcine
Budden Timothy
Mundra Piyushkumar
Gremel Gabriela
Akhras Victoria
Lin Lijing
Cook Martin
Kumar Rajiv
Grob Jean-Jacques
Nagore Eduardo
Marais Richard
Virós Amaya
Journal of The American Academy of Dermatology
2021
Identification of the chemical composition of six essential oils with mass spectroscopy and evaluation of their antibacterial and antioxidant potential
Nait Irahal Imane
Azzahra Lahlou Fatima
Hmimid Fouzia
Errami Ahmed
Guenaou Ismail
Diawara Idrissa
Kettani Halabi Mohamed
Fahde Sirine
Ouafik L'Houcine
Bourhim Noureddine
Flavour and Fragrance Journal
2021
High incidence of CDA deficiency in patients with hematological malignancies: perspectives and therapeutic implications
Donnette M.
Ciccolini J.
Pissier C.
Costello R.
Duffaud F.
Salas S.
Farnault L.
Tichadou A.
Arcani R.
Jarrot P.A.
Ouafik L.H.
Venton G.
Fanciullino R.
Ouafik L'Houcine
Annals of Oncology
2021
FP09.05 Driver Oncogenic Alterations and Indoor Radon in NSCLC Patients From the IFCT Biomarker Cohort: Bioradon France Study
Mezquita L.
Barlesi F.
Ielsch G.
Merlio J.
Debieuvre D.
Mosser J.
Ricordel C.
Ouafik L'Houcine
Rouquette I.
Monnet I.
Escande F.
Langlais A.
Morin F.
Vignaud C.
Auclin E.
Benitez J.C.
Planchard D.
Leuraud K.
Laurier D.
Besse B.
Westeel V.
Journal of Thoracic Oncology
2021
Targeting Adrenomedullin in Oncology: A Feasible Strategy With Potential as Much More Than an Alternative Anti-Angiogenic Therapy
Vázquez Ramiro
Riveiro Maria E
Berenguer-Daize Caroline
O’kane Anthony
Gormley Julie
Touzelet Olivier
Rezai Keyvan
Bekradda Mohamed
Ouafik L'Houcine
Frontiers in Oncology
2021
PTEN, ATM, IDH1 mutations and MAPK pathway activation as modulators of PFS and OS in patients treated by first line EGFR TKI, an ancillary study of the French Cooperative Thoracic Intergroup (IFCT) Biomarkers France project
Blons H.
Oudart J.-B.
Merlio J.-P.
Debieuvre D.
de Fraipont F.
Audigier-Valette C.
Escande F.
Hominal S.
Bringuier P-P
Fraboulet-Moreau S.
Ouafik L.
Moro-Sibilot D.
Lemoine A.
Langlais A
Missy P.
Morin F.
Souquet P.-J.
Barlesi F.
Cadranel J.
Beau-Faller M
Bringuier P.‐p.
Beau‐faller M.
Lung Cancer
2021
PTEN, ATM, IDH1 mutations and MAPK pathway activation as modulators of PFS and OS in patients treated by first line EGFR TKI, an ancillary study of the French Cooperative Thoracic Intergroup (IFCT) Biomarkers France project
Blons H.
Oudart J.-B.
Merlio J.-P.
Debieuvre D.
de Fraipont F.
Audigier-Valette C.
Escande F.
Hominal S.
Bringuier P-P
Fraboulet-Moreau S.
Ouafik L.
Moro-Sibilot D.
Lemoine A.
Langlais A
Missy P.
Morin F.
Souquet P.-J.
Barlesi F.
Cadranel J.
Beau-Faller M
Lung Cancer
2021
Cytoprotective effect of ethyl acetate fraction from Ephedra fragilis on H2O2-induced oxidative damage in Tetrahymena pyriformis
Guenaou Ismail
Hmimid Fouzia
Lahlou Fatima Azzahra
Errami Ahmed
Irahal Imane Nait
Fahde Sirine
Ouafik L'Houcine
Bourhim Noureddine
Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology
2021
Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study
Tomasini Pascale
Barlesi Fabrice
Gilles Sophie
Nanni-Metellus Isabelle
Soffietti Riccardo
Denicolai Emilie
Pellegrino Eric
Bialecki Emilie
Ouafik L'Houcine
Metellus Philippe
Oncotarget
2020
Outcomes of Patients With Advanced NSCLC From the Intergroupe Francophone de Cancérologie Thoracique Biomarkers France Study by KRAS Mutation Subtypes
Ruppert Anne-Marie
Beau-Faller Michèle
Debieuvre Didier
Ouafik L'Houcine
Westeel Virginie
Rouquette Isabelle
Mazières Julien
Bringuier Pierre-Paul
Monnet Isabelle
Escande Fabienne
Ricordel Charles
Merlio Jean-Philippe
Janicot Henri
Lemoine Antoinette
Foucher Pascal
Poudenx Michel
Morin Franck
Langlais Alexandra
Souquet Pierre-Jean
Barlesi Fabrice
Wislez Marie
JTO Clinical and Research Reports
2020
Adrenomedullin Blockade Induces Regression of Tumor Neovessels through Interference with Vascular Endothelial- Cadherin Signalling
Khalfaoui-Bendriss Ghizlane
Dussault Nadège
Fernandez-Sauze Samantha
Berenguer-Daize Caroline
Sigaud Romain
Delfino Christine
Cayol Mylène
Metellus Philippe
Chinot Olivier
Mabrouk Kamel
Ouafik Houcine
Prime Archives in Cancer Research
2020
Inequity in access to personalized medicine in France: Evidences from analysis of geo variations in the access to molecular profiling among advanced non-small-cell lung cancer patients: Results from the IFCT Biomarkers France Study
Kembou Nzale Samuel
Weeks William B
Ouafik L’houcine
Rouquette Isabelle
Beau-Faller Michèle
Lemoine Antoinette
Bringuier Pierre-Paul
Le Coroller Soriano Anne-Gaëlle
Barlesi Fabrice
Ventelou Bruno
PLoS ONE
2020
Independent prognostic value of ultra-sensitive quantification of tumor pre-treatment T790M subclones in EGFR mutated non-small cell lung cancer (NSCLC) treated by first/second generation TKI, depends on variant allele frequency (VAF): Results of the French cooperative thoracic intergroup (IFCT) biomarkers France project
Beau-Faller Michèle
Pencreach Erwan
Leduc Charlotte
Blons Hélène
Merlio Jean-Philippe
Bringuier Pierre-Paul
de Fraipont Florence
Escande Fabienne
Lemoine Antoinette
Ouafik L'Houcine
Denis Marc G.
Hofman Paul
Lacave Roger
Melaabi Samia
Langlais Alexandra
Missy Pascale
Morin Franck
Moro-Sibilot Denis
Barlesi Fabrice
Cadranel Jacques
Lung Cancer
2020
Independent prognostic value of ultra-sensitive quantification of tumor pre-treatment T790M subclones in EGFR mutated non-small cell lung cancer (NSCLC) treated by first/second generation TKI, depends on variant allele frequency (VAF): Results of the French cooperative thoracic intergroup (IFCT) biomarkers France project
Beau-Faller Michèle
Pencreach Erwan
Leduc Charlotte
Blons Hélène
Merlio Jean-Philippe
Bringuier Pierre-Paul
de Fraipont Florence
Escande Fabienne
Lemoine Antoinette
Ouafik L'Houcine
Denis Marc
Hofman Paul
Lacave Roger
Melaabi Samia
Langlais Alexandra
Missy Pascale
Morin Franck
Moro-Sibilot Denis
Barlesi Fabrice
Cadranel Jacques
Lung Cancer
2020
Simultaneous determination of cytosine arabinoside and its metabolite uracil arabinoside in human plasma by LC-MS/MS: Application to pharmacokinetics-pharmacogenetics pilot study in AML patients
Donnette Mélanie
Solas Caroline
Giocanti Madeleine
Venton Geoffroy
Farnault Laure
Berda-Haddad Yael
Hau Le Thi Thu
Costello Régis T
Ouafik L'Houcine
Lacarelle Bruno
Ciccolini Joseph
Fanciullino Raphaelle
Journal of Chromatography B Biomedical Sciences and Applications
2019
Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer
Civenni Gianluca
Bosotti Roberto
Timpanaro Andrea
Vàzquez Ramiro
Merulla Jessica
Pandit Shusil
Rossi Simona
Albino Domenico
Allegrini Sara
Mitra Abhishek
Mapelli Sarah
Vierling Luca
Giurdanella Martina
Marchetti Martina
Paganoni Alyssa
Rinaldi Andréa
Losa Marco
Mira-Catò Enrica
d'Antuono Rocco
Morone Diego
Rezaï Keyvan
d'Ambrosio Gioacchino
Ouafik L'Houcine
Mackenzie Sarah
Riveiro Maria
Cvitkovic Esteban
Carbone Giuseppina
Catapano Carlo
Cell Metabolism
2019
Lethal toxicities after capecitabine intake in a previously 5-FU-treated patient: why dose matters with dihydropryimidine dehydrogenase deficiency
Gbeto Crescent
Quaranta Sylvie
Mari Roxane
Fanciullino Raphaelle
Roche Catherine
Nahon Sophie
Solas Caroline
Ouafik L’houcine
Lacarelle Bruno
Allegre Thierry
Ciccolini Joseph
Pharmacogenomics
2019
Clinical outcomes of non–small-cell lung cancer patients with BRAF mutations: results from the French Cooperative Thoracic Intergroup biomarkers France study
Couraud Sébastien
Barlesi Fabrice
Fontaine-Deraluelle Clara
Debieuvre Didier
Merlio Jean-Philippe
Moreau Lionel
Beau-Faller Michèle
Veillon Rémi
Mosser Jean
Al Freijat Faraj
Bringuier Pierre-Paul
Lena Hervé
Ouafik L'Houcine
Westeel Virginie
Morel Alain
Audigier-Valette Clarisse
Missy Pascale
Langlais Alexandra
Morin Franck
Souquet Pierre-Jean
Planchard David
European Journal of Cancer
2019
Efficacy of Immune Checkpoint Inhibitors in KRAS-Mutant Non-Small Cell Lung Cancer (NSCLC)
Jeanson Arnaud
Tomasini Pascale
Souquet-Bressand Maxime
Brandone Nicolas
Boucekine Mohamed
Grangeon Mathieu
Chaleat Solène
Khobta Natalyia
Milia Julie
Mhanna Laurent
Greillier Laurent
Biemar Julie
Nanni Isabelle
Ouafik L’houcine
Garcia Stephane
Mazières Julie
Barlési Fabrice
Mascaux Céline
Journal of Thoracic Oncology
2019
Using Digital Droplet Polymerase Chain Reaction to Detect the Mosaic GNAS Mutations in Whole Blood DNA or Circulating Cell-Free DNA in Fibrous Dysplasia and McCune-Albright Syndrome
Romanet Pauline
Philibert Pascal
Fina Frederic
Cuny Thomas
Roche Catherine
Ouafik L'Houcine
Paris Françoise
Reynaud Rachel
Barlier Anne A.
The Journal of Pediatrics
2018
Detection of EGFR, KRAS and BRAF mutations in metastatic cells from cerebrospinal fluid
Frankel Diane
Nanni-Metellus Isabelle
Robaglia-Schlupp Andrée
Tomasini Pascale
Guinde Julien
Barlesi Fabrice
Astoul Philippe
Ouafik L’houcine
Amatore Florent
Secq Veronique
Kaspi Elise
Roll Patrice
Clinical Chemistry and Laboratory Medicine
2018