The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.
Comme chaque année les membres de l'INP participent à la semaine du cerveau. Parmi les actions de cette année on peut citer l'intervention de Cynthia et Charbel deux doctorants de l'équipe 9 qui sont allés rendre visite à l'école primaire du Pharo Catalans
In collaboration with the Holtzman lab., Maud Gratuze, with her colleagues Monica Xiong and Chao Wang, published an article on a project developed during her postdoc in the USA. In this study, entitled "Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy" and recently published in Molecular Neurodegeneration, they reduced ApoE4, the strongest genetic risk factor in Alzheimer’s disease, specifically derived from astrocytes in a mouse model of cerebral amyloid angiopathy.
INP and C2VN are organizing the next seminar in the framework of the seminar series of the Institute of Cancer and Immunology (ICI). This day will take place on Tuesday March 7th, 2023 on the Timone campus (Faculté des Sciences Médicales et Paramédicales, amphi 4). We will have the pleasure to welcome Pr Etienne Meylan (PhD, Belgium) who will be giving a seminar entitled "Tumor-associated neutrophils in the immunotherapy era". His research work focuses on neutrophils and lung cancer.
INP, more precisely PINT platform, along with 13 laboratories and institutes affiliated with AMU (*) is co-organizing the 3rd Integrative Structural Biology meeting (BSI 2023) with the Association Française de Cristallographie (AFC) and the Société Française de Biophysique (SFB). The meeting will take place in Marseille in the Faculty of Medical Sciences on the Timone Campus on November 13-17, 2023.
Save the date and follow us on Twitter (@BSI2023) for updated information!
INP, Molecular Interaction & Pharmacology (team 9) and GlioME: Gliomagenesis and MicroEnvironment (team 8) are glad to share the release of their new work "Plasma nanoDSF Denaturation Profile at Baseline Is Predictive of Glioblastoma EGFR Status" which was done in collaboration with data scientists from Laboratoire Hubert Curien, UJM-Saint-Etienne and Laborat
On december 10th 2022, PINT INP and Vect-Horus members met in the Hippodrome Borély for the "Course des Lumières" organized by Foundation Recherche Alzheimer. It was freezing but together with 600 or something others, they walked 5 km or ran 8 km, to light up the night against Alzheimer's disease and for all patients, carrying a luminous object. See a few pictures below
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The Cancéropole PACA has created a web page for the PETRA platform with all the necessary information and the contact form: PETRA web page.
The SynapTau team is thrilled to announce the publication of our collaborative work. This has been an incredible partnership, and we are delighted to share our findings in the journal Life Science Alliance! In this paper, we demonstrated that parenchymal border macrophages (PBMs) function impedes tau pathology and tau-mediated neurodegeneration, while tau pathology promotes PBM dysfunction associated with impaired CSF flow. Our results identify PBMs as novel cellular regulators of tau pathology and tau-mediated neurodegeneration.
The GlioME Team has new publication out in International Journal of Molecular Sciences as part of the Special Issue « Emerging Therapies for Glioblastoma ». This article deals with one of the team’s key issues, the gangliosides recognized by the A2B5 antibody and used as biomarker of cancer stem cells (CSC) in glioblastoma human brain tumours.
On July 6, 5 INP members took part in the first Ma Terre en 180' workshop organized by Louise Greetham (Team 6/SCENT) and Santiago Rivera (Team 1). MT 180' is the 1st collaborative workshop from the academic world to build scenarios for reducing carbon footprint within a research laboratory. Congratulations to Fanny (aka Maggie), Laure (aka Zara), Theresa (aka Claire), Géraldine (aka David) and Ivan (aka Benjamin) for their participation and commitment.
Since the first event in Marseille in 2013, initiated by François Devred and Stéphane Honoré, the French microtubule network has been organizing colloquia bringing together researchers, post-docs and students from more than 34 laboratories, every 2 years in a different city. After Grenoble (2015), Versailles (2017), and Rennes (2019), the fifth edition of the congress of french scientists working on microtubules took place on June 29 and 30, 2023 in Montpellier.
The GlioME team was delighted to take part in the tumoroids workshop at the summerschool organized by the Institute of Cancer and Immunology. For one day, the team welcomed 8 international students to introduce them to the preparation of human glioblastoma tumoroids. A day rich in scientific and human exchanges.