The Institute of NeuroPhysiopathology (INP) is a training and research centre of excellence that combines basic and translational research to study neural cell organisation, function and interaction, the molecular and cellular bases of major brain diseases, and to develop innovative cellular and molecular therapeutic strategies.
Teams
NeuroTimone Facility (PFNT)
The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.
News
-
Zoom sur la 5ème édition de la classification de l'OMS des tumeurs du Système Nerveux CentralMembre expert du comité éditorial et co-auteur de plusieurs chapitres de la 5ème édition de la Classification des tumeurs du SNC de l’OMS parue le 12 novembre dernier, Dominique Figarella-Branger (Equipe 8 GlioME) a dirigé la rédaction d'un article de revue en français sur cette nouvelle classification, récemment publié dans les Annales de Pathologie: https://authors.elsevier.com/c/1eB1VtB1GOhjB
Un article de référence, facile d'accès, pour toute personne souhaitant être à la page sur la classification des tumeurs du SNC!
-
Recent works on Zinc binding to S100A1 and to NCS-1 published in Biomolecules and in International Journal of Molecular Sciences respectivelyTeam 9 (Cytoskeleton and Neurophysiopathology) and platform PINT (platform interactive Timone) are happy to see the almost simultaneous publications of two papers about about the impact of Zn2+ binding to NCS1 and to S100A1 respectively with their collaborators from Belozersky Institute of Physico Chemical Biology, Lomonosov Moscow State University, while the third one about Tau protein Zn2+ binding sites has been under review for already 3 months ...
-
New publication in Science Reports from Team 10 -
Tau & Glioma : new article from INP team 9 and team 8 in CancersThe Cytoskeleton & Neurophysiopathology team and the GlioME team have a new publication out! Published on November 19th in Cancers, this article gives insights into how Tau regulates glioblastoma progression, via the PI3K-AKT signaling pathway.
Read the article here: https://www.mdpi.com/2072-6694/13/22/5818
-
INP participation to AMU's 1st Digital Sciences and AI for Health conferenceOn November 25 and 26, the conference "Digital Sciences and Artificial Intelligence for Health at Aix-Marseille University" was held in the Grisoli amphitheater & the Great Hall of the Faculty of Medical and Paramedical Sciences - Timone.
The aim of this conference was to formally bring together for the first time all the actors of Aix-Marseille University and the University Hospital Center involved in the digital and AI/health field, whether they are clinicians or theoreticians.
-
L'institut TranceScience, présidé par François Féron, dans Le MondePlusieurs chercheurs de la communauté marseillaise des neurosciences, notamment l’équipe d’Agnès Trébuchon, mènent des recherches sur les fondamentaux et les effets thérapeutiques de la transe cognitive auto-induite. Tout comme l’hypnose ou la méditation, il s’agit d’un état modifié de conscience, induit par la seule volonté de chacun. A l’occasion de la création par Paris VIII du premier diplôme universitaire (DU/DESU) sur cette pratique, Le Monde a consacré une double page aux recherches menées par l’Institut international de recherches sur la transe (TranceScience), présidé par François Féron (équipe NOSE, INP)
-
New Post-doctoral fellow in team 1Neural Plasticity and Degeneration team has recently welcomed Shweta SONAWANE.
Shweta is from Mumbai (India) she did her Ph.D. at the Biochemical sciences division of CSIR - National Chemical Laboratory in Pune (India).
Her doctoral research was largely focused on Tau pathology in Alzheimer’s disease studying in particular the effect of glycated and phosphorylated Tau on cytoskeleton integrity as well as aggregation propensity in order to find small molecules that could attenuate Tau aggregation and prevent its glycation.
-
Just out: NeuroCyto team in ScienceThe NeuroCyto team has a new publication out! Published on November 5th in Science, this article elucidates how adenosine A2A receptors drive removal of inhibitory synapses depending on their activity. This is a fruitful collaboration with the labs of Sabine Lévi at Institut du Fer à Moulin (IFM) in Paris and Christophe Bernard at Institut de Neuroscience des Systèmes (INS) in Marseille. Read the article here: https://www.science.org/doi/10.1126/science.abk2055
Pages
INP in numbers
- 126 members
- 44 researchers
- 48 research assistants
- 12 post-docs
- 11 PhD
MEDIM 2022 - retour d'expérience
Du lundi 24 au vendredi 29 avril s'est tenue, toujours avec succès, la deuxième édition de la formation MedIM (Méthodes d'étude des Interactions Moléculaires) co-organisée par la Plateforme INteractome Timone (PINT) de l’INP, la plateforme de Biologie Structurale de l’AFMB et les plateformes de l’IMM, toutes trois labellisées "Plateformes Technologiques du site d'Aix-Marseille".
L'équipe GlioME et la plateforme PINT mobilisées lors de l'assemblée générale de l'association ARTC Sud
Emmanuel Snacel-Fazy, doctorant dans l'équipe Gliome et François Devred co-directeur de la plateforme PINT ont présenté leurs travaux lors de l'assemblée générale de l'Association pour la Recherche sur les Tumeurs Cérébrales (ARTC Sud).
Séminaire Nicola Allen - "Astrocyte regulation of neuronal synapses"
Nicola Allen - Associate Professor at the Molecular Neurobiology Laboratory of the Salk Institute for Biological Studies in La Jolla, USA - est l'invitée de Neuroschool ce mois-ci pour un séminaire sur son domaine de recherche: "Astrocyte regulation of neuronal synapses". Dr Allen viendra donner son séminaire le 13 mai 2022 à 14h30 à l'amphithéâtre du CERIMED, sur le campus de la Timone (vue aérienne).
Congratulations to Chiara who won a poster prize
Chiara Bastiancich, Post-doc in the GlioME team presented her ongoing GlioRET project at the European Symposium on Controlled Drug Delivery.
Her poster "Elucidating the tumor resection microenvironment of glioblastoma toward the development of fit-for-purpose local treatments" won over the cogress jury !
Another award for Emmanuel Snacel-Fazy
Emmanuel Snacel-Fazy, a 2nd year doctoral student in the GlioME team, won the best poster award at yesterday's "Conference Annuelle de L'institut Cancer et Immunologie (ICI)", Thursday 31 March 2022.
His work on the "Remodelling of the glioblastoma immune landscape by smac mimetic GDC-0152" has been appreciated and rewarded. Once again, congratulations!
Two New articles from GlioME team
Dr Romain Appay, pathologist at the Timone Hospital and PhD student in the GioME team, has published a new research paper entitled "Rosette-forming glioneuronal tumours are midline, FGFR1- mutated tumours" in the Neuropathology and Applied Neurobiology journal.
New article from NPD Team 1 published in the Journal of Neuroinflammation
The latest article for NPD team 1 has been published this month into the Journal of Neuroinflammation.
Membrane-type matrix metalloproteinase 5 (MT5-MMP) deficiency in the 5xFAD mouse model of Alzheimer's disease reduces brain neuroinflammation along with amyloidosis, and prevents deficits in synaptic activity and cognition in prodromal stages of the disease. In addition, MT5-MMP deficiency prevents interleukin-1 beta (IL-1β)-mediated inflammation in the peripheral nervous system.
Emmanuel Nivet on Neuro'binar - March 22nd 1pm
Don't miss the next Neuro'binar of NeuroMarseille with Emmanuel Nivet (Team 6) !
Next Tuesday, on March 22nd, 2022, at 1 pm online, discover Dr Emmanuel Nivet's work in the 13th edition of Neuro'binar:
🔘 Emmanuel Nivet (INP) will present his research topic entitled: "Human induced pluripotent stem cells to study the role of astrocytes in Alzheimer’s disease"
Partners
Aix Marseille Université | All rights reserved - Legal notice