Dominika Pilat (team 1) PhD defense
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The Institute of NeuroPhysiopathology (INP) is a training and research centre of excellence that combines basic and translational research to study neural cell organisation, function and interaction, the molecular and cellular bases of major brain diseases, and to develop innovative cellular and molecular therapeutic strategies.
Teams
NeuroTimone Facility (PFNT)
The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.
News
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INP participation to AMU's 1st Digital Sciences and AI for Health conferenceOn November 25 and 26, the conference "Digital Sciences and Artificial Intelligence for Health at Aix-Marseille University" was held in the Grisoli amphitheater & the Great Hall of the Faculty of Medical and Paramedical Sciences - Timone.
The aim of this conference was to formally bring together for the first time all the actors of Aix-Marseille University and the University Hospital Center involved in the digital and AI/health field, whether they are clinicians or theoreticians.
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L'institut TranceScience, présidé par François Féron, dans Le MondePlusieurs chercheurs de la communauté marseillaise des neurosciences, notamment l’équipe d’Agnès Trébuchon, mènent des recherches sur les fondamentaux et les effets thérapeutiques de la transe cognitive auto-induite. Tout comme l’hypnose ou la méditation, il s’agit d’un état modifié de conscience, induit par la seule volonté de chacun. A l’occasion de la création par Paris VIII du premier diplôme universitaire (DU/DESU) sur cette pratique, Le Monde a consacré une double page aux recherches menées par l’Institut international de recherches sur la transe (TranceScience), présidé par François Féron (équipe NOSE, INP)
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New publication in Frontiers in Oncology from Team 10 -
New Post-doctoral fellow in team 1Neural Plasticity and Degeneration team has recently welcomed Shweta SONAWANE.
Shweta is from Mumbai (India) she did her Ph.D. at the Biochemical sciences division of CSIR - National Chemical Laboratory in Pune (India).
Her doctoral research was largely focused on Tau pathology in Alzheimer’s disease studying in particular the effect of glycated and phosphorylated Tau on cytoskeleton integrity as well as aggregation propensity in order to find small molecules that could attenuate Tau aggregation and prevent its glycation.
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Just out: NeuroCyto team in ScienceThe NeuroCyto team has a new publication out! Published on November 5th in Science, this article elucidates how adenosine A2A receptors drive removal of inhibitory synapses depending on their activity. This is a fruitful collaboration with the labs of Sabine Lévi at Institut du Fer à Moulin (IFM) in Paris and Christophe Bernard at Institut de Neuroscience des Systèmes (INS) in Marseille. Read the article here: https://www.science.org/doi/10.1126/science.abk2055
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New article from the NeuroCyto Team in NeuronThe NeuroCyto team has a new publication out! Published on Sep. 15 in Neuron, this article reveals how clathrin is slowly transported along axons by forming transport packets that are then docked at presynapses where they can dynamically supply clathrin for synaptic function. This is another episode of the long-standing collaboration between the NeuroCyto team and the lab of Subhojit Roy at UCSD. Read the article here: https://doi.org/10.1016/j.neuron.2021.08.016
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La magie de la fée bleue a une fois de plus opéréNadia Coliac a été l’auteure, metteuse en scène et scénographe d’une expérience théâtrale bioluminescente qui a eu lieu le 19 octobre dernier à Paris sur la scène des arts et des sciences du théâtre de la Reine Blanche. Une expérience grandeur nature d'éclairer tout un théâtre uniquement avec la lumière vivante qui a captivé le public, ce fut un moment magique !
Cette production artistique et scientifique fait partie de ses recherches dans le domaine de l'histoire des sciences pour réhabiliter la mémoire de " Raphaël Dubois génie de la lampe vivante".
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NanoDSF goes high throughput thanks to NT.Robotic AutosamplerPINT platform recently acquired the NT.Robotic Autosampler that complemented the existing Prometheus NT.Plex nanoDSF instrument which is already equipped with aggregation detection optics to get complete stability characterization.
NT.Robotic Autosampler is a stand-alone, all-inclusive system with robotic arm, computer, and monitor. PINT is now able to analyze up to 1,536 samples for hands-free characterization of thermal unfolding and chemical denaturation in a single experiment. Incorporate plate temperature control to keep your samples at 4 to 20 °C while they wait in the queue.
This will permit to scale up the existing applications of the Prometheus :
Pages
INP in numbers
- 126 members
- 44 researchers
- 48 research assistants
- 12 post-docs
- 11 PhD
Recent works on Zinc binding to S100A1 and to NCS-1 published in Biomolecules and in International Journal of Molecular Sciences respectively
Team 9 (Cytoskeleton and Neurophysiopathology) and platform PINT (platform interactive Timone) are happy to see the almost simultaneous publications of two papers about about the impact of Zn2+ binding to NCS1 and to S100A1 respectively with their collaborators from Belozersky Institute of Physico Chemical Biology, Lomonosov Moscow State University, while the third one about Tau protein Zn2+ binding sites has been under review for already 3 months ...
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Poste pourvu : Ingénieur - CDD de 12 mois
Mission : Etudier le rôle des gènes X et Z dans l’agressivité et la résistance au traitement du glioblastome
Etablissement d’accueil : Equipe 8 GlioME (Gliomagenèse et MicroEnvironnement) – Institut de Neurophysiopathologie - Faculté de Médecine Timone - MARSEILLE
Site web : https://inp.univ-amu.fr/en/teams/gliome-gliomagenesis-and-microenvironment
English
New publication in Frontiers in Oncology
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Tau & Glioma : new article from INP team 9 and team 8 in Cancers
The Cytoskeleton & Neurophysiopathology team and the GlioME team have a new publication out! Published on November 19th in Cancers, this article gives insights into how Tau regulates glioblastoma progression, via the PI3K-AKT signaling pathway.
Read the article here: https://www.mdpi.com/2072-6694/13/22/5818
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INP participation to AMU's 1st Digital Sciences and AI for Health conference
On November 25 and 26, the conference "Digital Sciences and Artificial Intelligence for Health at Aix-Marseille University" was held in the Grisoli amphitheater & the Great Hall of the Faculty of Medical and Paramedical Sciences - Timone.
The aim of this conference was to formally bring together for the first time all the actors of Aix-Marseille University and the University Hospital Center involved in the digital and AI/health field, whether they are clinicians or theoreticians.
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L'institut TranceScience, présidé par François Féron, dans Le Monde
Plusieurs chercheurs de la communauté marseillaise des neurosciences, notamment l’équipe d’Agnès Trébuchon, mènent des recherches sur les fondamentaux et les effets thérapeutiques de la transe cognitive auto-induite. Tout comme l’hypnose ou la méditation, il s’agit d’un état modifié de conscience, induit par la seule volonté de chacun.
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New Post-doctoral fellow in team 1
Neural Plasticity and Degeneration team has recently welcomed Shweta SONAWANE.
Shweta is from Mumbai (India) she did her Ph.D. at the Biochemical sciences division of CSIR - National Chemical Laboratory in Pune (India).
Her doctoral research was largely focused on Tau pathology in Alzheimer’s disease studying in particular the effect of glycated and phosphorylated Tau on cytoskeleton integrity as well as aggregation propensity in order to find small molecules that could attenuate Tau aggregation and prevent its glycation.
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