L'INP a participé au 7èmes journées scientifiques francophones du CALM qui étaient organisées par le Le Club Alzheimer de Montpellier les mardi 14 et mercredi 15 Novembre 2023, en distanciel et en présentiel. Au cours de ces 2 journées qui ont pour objectif de de dynamiser les échanges entre les chercheurs et cliniciens travaillant sur la maladie d'Alzheimer, Maud GRATUZE (équipe 2') a donné une conférence intitulée "Les macrophages de la bordure parenchymateuse : des cellules immunitaires qui régulent la pathologie tau et la neurodégénérescence associée" dans

The latest collaboration from the NeuroCyto team was just published in the Journal of Cell Science, and asks a simple question: how do microtubule and actin fight or cooperate with each other? The CytoMorpho lab of Manuel Théry and Laurent Blanchoin in Paris and Grenoble used complex in-vitro reconstitution to show how dense actin networks can stop microtubule growth.

Super-resolution microscopy is super-nice, but it can also be super-expensive or super-complicated. But now it's super-simple to get nanoscale details of your favorite cells with any kind of microscope, thanks to the enhanced version of the SRRF algorithm just published in Nature Methods!

🎉 Congratulations to Emmanuel Snacel-Fazy, who brilliantly defended his thesis and was awarded the title of Docteur en biologie-santé, spécialité oncologie d'Aix-Marseille Université, with the congratulations of the jury. 

Emmanuel is now an ATER in the GlioME team and is continuing the technological development of light-sheet imaging associated with the clearing technique he developed. 

The NeuroCyto team published their latest work in the Journal of Cell Biology (article is available here), where they reveal the presence of distinct actin nanostructures within presynapses. The article is featured in the October issue of the journal, and made it to the cover that shows a nice picture of a neuron endogenously tagged for actin using CRISPR/Cas9.

Alessandra Pagano, a teacher-researcher in the GlioME team, recently obtained "emergence" funding from the Cancéropôle PACA for her project entitled: GeNI project "Generation of a new class of drugs targeting ML-IAP to improve glioblastoma treatment".

The GlioME team is happy to share the latest article entitled "Local delivery of doxorubicin prodrug via lipid nanocapsule–based hydrogel for the treatment of glioblastoma", published in the journal Drug Delivery and Translational Research!

This work was realised in collaboration between three affiliations: Université catholique de Louvain, Institute of NeuroPhysiopathology (INP) and Dipartimento di Scienza e Tecnologia del Farmaco - Università di Torino.

The NeuroCyto team published a new article in Cell Reports Methods. This is the work of PhD student Karoline Friedl in collaboration with the Abbelight company: we thoroughly characterized two different modalities of simultaneous multicolor Single Molecule Localization Microscopy using a two-camera module. The article can be found here (open access).