NeuroTimone Facility (PFNT)

The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.

News

  1. Welcome to Mensah, a new Master 2 student in team 10 !

    Our team is pleased to welcome Mensah Loko for a 6 months Master internship (from November 2022) in Integrative Biology and Physiology: Integrative approach to the functions of life: from gene to pathology. The subject of his internship is the role of Adrenomedullin expressed by glioblastoma-associated endothelial cells in promoting a stable and functional angiogenesis.

  2. 3 first author papers for team 9 three PhD students

    We are happy to celebrate the release of 3 first author papers on Myotoxin-3 from a snake venom as a new microtubule targeting agent, on the mechanism of action of Zinc induced aggregation of tau, and a review article on tau as a therapeutic target for cancer, for team 9 three PhD students : Cecilia, Dahbia and Rayane, this month :

  3. Welcome to Clara Camilla, New PhD student in team 10

    Clara Camilla, PhD student, Biology-Health - Oncology speciality, is starting her thesis on the theme: "Evaluation of Longitudinal Genomic Alterations in Diffuse Low Grade Gliomas in Adults".

  4. The GlioME team has obtained a "Action Structurante" funding for the creation of the PETRA facility

    Emeline Tabouret and Aurélie Tchoghandjian, in collaboration with Thierry Virolle's team at the l'Institut de Biologie Valrose in Nice, are among the two winners to have obtained "Action structurante" funding from the Cancéropôle PACA.

    This funding aims to structure the neuro-oncology at the preclinical and translational level in the region (between Marseille and Nice) and will be used to create the PETRA (PrEclinical and TRAnslational Research) platform on these two sites.

  5. New publication from the GlioME team

    Chiara Bastiancich published the last article of her first postdoc on GRAVITY project 🎉
    The challenging goal was: delivering to the brain metallic nanoparticles via focused ultrasound-mediated blood-brain barrier (BBB) permeabilization, to heat them using lasers for glioblastoma photothermal therapy! In this paper she shows one of the steps to reach this daunting task.

    ==> Molecular Imaging of Ultrasound-Mediated Blood-Brain Barrier Disruption in a Mouse Orthotopic Glioblastoma Model

  6. New publication from PINT facility in Cellular and Molecular Life Sciences

    Géraldine Ferracci (Study Engineer on the PINT platform) participated in the publication entitled "Molecular landscape of BoNT/B bound to a membrane inserted synaptotagmin/ganglioside complex" which appeared on August 25, 2022 in Cellular and Molecular Life Sciences.

    Abstract :

  7. Pôle spectrométrie de masse de la plateforme PINT

    Après une période transitoire où il est resté sur le site de la faculté Nord, le spectromètre de masse de l'INP (Thermo Scientific Q-exactive) est arrivé sur le site Timone cet été. Maya Belghazi ayant quitté l'INP pour rejoindre l'IMM, Claude Villard est dorénavant votre seul interlocuteur pour les projets en lien avec cet appareil.

  8. Zinc Modulation of Neuronal Calcium Sensor Proteins: Three Modes of Interaction with Different Structural Outcomes

    Congratulation to Vika post doc in team 9 (Cytoskeleton and NeuroPhysiopathology) for this great piece of work on Zinc Modulation of 3 families of Neuronal Calcium Sensor Proteins recently published in Biomolecules.

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INP in numbers

  • 126 members
  • 44 researchers
  • 48 research assistants
  • 12 post-docs
  • 11 PhD

 

ICI research seminar & master class : Pr Etienne Meylan

INP and C2VN are organizing the next seminar in the framework of the seminar series of the Institute of Cancer and Immunology (ICI). This day will take place on Tuesday March 7th, 2023 on the Timone campus (Faculté des Sciences Médicales et Paramédicales, amphi 4). We will have the pleasure to welcome Pr Etienne Meylan (PhD, Belgium) who will be giving a seminar entitled "Tumor-associated neutrophils in the immunotherapy era". His research work focuses on neutrophils and lung cancer.

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BSI2023 : 3rd Integrative Structural Biology meeting in Marseille

INP, more precisely PINT platform, along with 13 laboratories and institutes affiliated with AMU (*) is co-organizing the 3rd Integrative Structural Biology meeting (BSI 2023) with the Association Française de Cristallographie (AFC) and the Société Française de Biophysique (SFB). The meeting will take place in Marseille in the Faculty of Medical Sciences on the Timone Campus on November 13-17, 2023.

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INP Team 8 and 9 joint publication : Plasma nanoDSF Denaturation Profile at Baseline Is Predictive of Glioblastoma EGFR Status

INP, Molecular Interaction & Pharmacology (team 9) and GlioME: Gliomagenesis and MicroEnvironment (team 8) are glad to share the release of their new work "Plasma nanoDSF Denaturation Profile at Baseline Is Predictive of Glioblastoma EGFR Status" which was done in collaboration with data scientists from 

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