OUAFIK L'houssine
Onglets principaux
Team
Localisation
Faculté des Sciences Médicales et Paramédicales couloir vert 3ème étage
Publications
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Extreme Gradient Boosting Tuned with Metaheuristic Algorithms for Predicting Myeloid NGS Onco-Somatic Variant PathogenicityBioengineering2023
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Impact of Molecular Biology in Diagnosis, Prognosis, and Therapeutic Management of BCR::ABL1-Negative Myeloproliferative NeoplasmCells2023
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Adrenomedullin Secreted by Melanoma Cells Promotes Melanoma Tumor Growth through Angiogenesis and LymphangiogenesisCancers2022
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1693P Incidence of NTRK genes fusion in adult brain tumours: A prospective cohort of 140 patients with cerebral gliomas and brain metastasesAnnals of Oncology2022
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1693P Incidence of NTRK genes fusion in adult brain tumours: A prospective cohort of 140 patients with cerebral gliomas and brain metastases2022
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Deep Learning Architecture Optimization with Metaheuristic Algorithms for Predicting BRCA1/BRCA2 Pathogenicity NGS AnalysisBioMedInformatics2022
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Machine learning random forest for predicting oncosomatic variant NGS analysisScientific Reports2021
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Role of the Tyrosine Phosphatase SHP-2 in Mediating Adrenomedullin Proangiogenic Activity in Solid TumorsFrontiers in Oncology2021
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Identification of the chemical composition of six essential oils with mass spectroscopy and evaluation of their antibacterial and antioxidant potentialFlavour and Fragrance Journal2021
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Molecular characterization of fast-growing melanomasJournal of The American Academy of Dermatology2021
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High incidence of CDA deficiency in patients with hematological malignancies: perspectives and therapeutic implicationsAnnals of Oncology2021
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FP09.05 Driver Oncogenic Alterations and Indoor Radon in NSCLC Patients From the IFCT Biomarker Cohort: Bioradon France StudyJournal of Thoracic Oncology2021
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Targeting Adrenomedullin in Oncology: A Feasible Strategy With Potential as Much More Than an Alternative Anti-Angiogenic TherapyFrontiers in Oncology2021
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PTEN, ATM, IDH1 mutations and MAPK pathway activation as modulators of PFS and OS in patients treated by first line EGFR TKI, an ancillary study of the French Cooperative Thoracic Intergroup (IFCT) Biomarkers France projectLung Cancer2021
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Cytoprotective effect of ethyl acetate fraction from Ephedra fragilis on H2O2-induced oxidative damage in Tetrahymena pyriformisComparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology2021
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Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot studyOncotarget2020
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Outcomes of Patients With Advanced NSCLC From the Intergroupe Francophone de Cancérologie Thoracique Biomarkers France Study by KRAS Mutation SubtypesJTO Clinical and Research Reports2020
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Adrenomedullin Blockade Induces Regression of Tumor Neovessels through Interference with Vascular Endothelial- Cadherin SignallingPrime Archives in Cancer Research2020
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Inequity in access to personalized medicine in France: Evidences from analysis of geo variations in the access to molecular profiling among advanced non-small-cell lung cancer patients: Results from the IFCT Biomarkers France StudyPLoS ONE2020
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Independent prognostic value of ultra-sensitive quantification of tumor pre-treatment T790M subclones in EGFR mutated non-small cell lung cancer (NSCLC) treated by first/second generation TKI, depends on variant allele frequency (VAF): Results of the French cooperative thoracic intergroup (IFCT) biomarkers France projectLung Cancer2020
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Independent prognostic value of ultra-sensitive quantification of tumor pre-treatment T790M subclones in EGFR mutated non-small cell lung cancer (NSCLC) treated by first/second generation TKI, depends on variant allele frequency (VAF): Results of the French cooperative thoracic intergroup (IFCT) biomarkers France projectLung Cancer2020
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Simultaneous determination of cytosine arabinoside and its metabolite uracil arabinoside in human plasma by LC-MS/MS: Application to pharmacokinetics-pharmacogenetics pilot study in AML patientsJournal of Chromatography B Biomedical Sciences and Applications2019
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Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate CancerCell Metabolism2019
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Lethal toxicities after capecitabine intake in a previously 5-FU-treated patient: why dose matters with dihydropryimidine dehydrogenase deficiencyPharmacogenomics2019
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Clinical outcomes of non–small-cell lung cancer patients with BRAF mutations: results from the French Cooperative Thoracic Intergroup biomarkers France studyEuropean Journal of Cancer2019
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Efficacy of Immune Checkpoint Inhibitors in KRAS-Mutant Non-Small Cell Lung Cancer (NSCLC)Journal of Thoracic Oncology2019
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Using Digital Droplet Polymerase Chain Reaction to Detect the Mosaic GNAS Mutations in Whole Blood DNA or Circulating Cell-Free DNA in Fibrous Dysplasia and McCune-Albright SyndromeThe Journal of Pediatrics2018
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Detection of EGFR, KRAS and BRAF mutations in metastatic cells from cerebrospinal fluidClinical Chemistry and Laboratory Medicine2018
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CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabineBlood Advances2018
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Proof of concept: prognostic value of the plasmatic concentration of circulating cell free DNA in desmoid tumors using ddPCROncotarget2018
