Pediatric Patients With Solid or Hematological Tumor Disease: Vancomycin Population Pharmacokinetics and Dosage Optimization.


  • Guilhaumou Romain
  • Marsot Amelie
  • Dupouey Julien
  • Galambrun Claire
  • Boulamery Audrey
  • Coze Carole
  • Simon Nicolas
  • André Nicolas

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In pediatric cancer patients, determination of optimal vancomycin dosage is essential because of high risk of inadequate concentrations and bacterial resistance. The aim of this study was to determine vancomycin pharmacokinetic parameters in this population and propose dosage optimization to achieve optimal concentration.

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