NeuroTimone Facility (PFNT)

The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.

News

  1. Welcome to Clara Camilla, New PhD student in team 10

    Clara Camilla, PhD student, Biology-Health - Oncology speciality, is starting her thesis on the theme: "Evaluation of Longitudinal Genomic Alterations in Diffuse Low Grade Gliomas in Adults".

  2. The GlioME team has obtained a "Action Structurante" funding for the creation of the PETRA facility

    Emeline Tabouret and Aurélie Tchoghandjian, in collaboration with Thierry Virolle's team at the l'Institut de Biologie Valrose in Nice, are among the two winners to have obtained "Action structurante" funding from the Cancéropôle PACA.

    This funding aims to structure the neuro-oncology at the preclinical and translational level in the region (between Marseille and Nice) and will be used to create the PETRA (PrEclinical and TRAnslational Research) platform on these two sites.

  3. New publication from the GlioME team

    Chiara Bastiancich published the last article of her first postdoc on GRAVITY project 🎉
    The challenging goal was: delivering to the brain metallic nanoparticles via focused ultrasound-mediated blood-brain barrier (BBB) permeabilization, to heat them using lasers for glioblastoma photothermal therapy! In this paper she shows one of the steps to reach this daunting task.

    ==> Molecular Imaging of Ultrasound-Mediated Blood-Brain Barrier Disruption in a Mouse Orthotopic Glioblastoma Model

  4. New publication from PINT facility in Cellular and Molecular Life Sciences

    Géraldine Ferracci (Study Engineer on the PINT platform) participated in the publication entitled "Molecular landscape of BoNT/B bound to a membrane inserted synaptotagmin/ganglioside complex" which appeared on August 25, 2022 in Cellular and Molecular Life Sciences.

    Abstract :

  5. Pôle spectrométrie de masse de la plateforme PINT

    Après une période transitoire où il est resté sur le site de la faculté Nord, le spectromètre de masse de l'INP (Thermo Scientific Q-exactive) est arrivé sur le site Timone cet été. Maya Belghazi ayant quitté l'INP pour rejoindre l'IMM, Claude Villard est dorénavant votre seul interlocuteur pour les projets en lien avec cet appareil.

  6. Zinc Modulation of Neuronal Calcium Sensor Proteins: Three Modes of Interaction with Different Structural Outcomes

    Congratulation to Vika post doc in team 9 (Cytoskeleton and NeuroPhysiopathology) for this great piece of work on Zinc Modulation of 3 families of Neuronal Calcium Sensor Proteins recently published in Biomolecules.

  7. Opening of the Nikon Center of Excellence for Neuro-NanoImaging at INP

    After being postponed in 2021, the inauguration of the Nikon Center of Excellence for Neuro-Nanoimaging at Aix-Marseille Université (see more details on the Center of Excellence below) will take place on September 22, 2022 starting at 9:00 am on the Timone campus (Grisoli amphitheater), in the presence of the President of AMU Mr. Eric Berton and the Director of Nikon Europe Mr. Takaharu Sasaoka. We are pleased to invite you to this event which will combine an international scientific symposium, followed by an inauguration ceremony and the possibility to visit the platform (see attached program).

  8. Team 6 (Nivet) at NeuroMarseille's Day

    Team 6 was happy to participate in NeuroMarseille's day, which took place on June 28, 2022.

    Many members of the INP attended this scientific and friendly day for the neuroscience community. 

    Our M1 student, Marine Dos Santos, also presented her one-month work in our team, during the afternoon poster session. 

    We thank NeuroMarseille for this great day !

     

     

     

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INP in numbers

  • 126 members
  • 44 researchers
  • 48 research assistants
  • 12 post-docs
  • 11 PhD

 

Financement Canceropole : Repositionnement de molécules en prématuration

Le projet « Validation de nouveaux agents ciblant les microtubules et pouvant traverser la barrière hémato-encéphalique pour le traitement du glioblastome » déposé à l’appel « Repositionnement de molécules en prématuration » du Canceropôle Provence Alpes Côte d’Azur par Philipp Tsvetkov (plateforme PINT) a été retenu par le Comité Scientifique du Canceropole PACA pour être financé à hauteur de 30 000 euros. Sont impliquées dans ce projet les équipes 9 et 8 et leurs plateformes associées respectives

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CMA-CGM funding obtained by Team 8

Team 8 has recently obtained a CMA-CGM funding in the framework of the call for projects "Programme d'équipement et de recherche clinique" 2022

The project title is "Program of Precision RAdioTherapy to Improve patient Cancer treatment" and aims to participate in the purchase of a small animal irradiator "SARRP" that will complement the pre-clinical offerings of the PETRA network.

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Amidex Blanc funding of a collaborative project between teams 8 and 9

 

Team 9 represented by José Luis and team 8 represented by Aurélie Tchoghandjian have obtained Amidex Blanc funding for the project: "Bioinspired cytotoxic copper complexes: deciphering their mechanism of action in cancer cells to develop efficient therapeutic agents (CytoCu4Cancer)".

This project is led by a chemist, Olga Iranzo of the Institute of Molecular Sciences of Marseille (iSm2).

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Tous et toutes au recyclage !

Depuis lundi 3 Avril, l'INP participe à une opération inter-laboratoires de quantification de déchets recyclables professionnels (et ménagers) sur le campus Timone. 
Pour cela, chaque aile a été aménagée avec des points de collecte et de tri sélectif. Chaque semaine, les différentes catégories seront pesées puis emmenées au recyclage pour valorisation. 

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Maud Gratuze, new team leader, first INP publication

In collaboration with the Holtzman lab., Maud Gratuze, with her colleagues Monica Xiong and Chao Wang, published an article on a project developed during her postdoc in the USA. In this study, entitled "Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy" and recently published in Molecular Neurodegeneration, they reduced ApoE4, the strongest genetic risk factor in Alzheimer’s disease, specifically derived from astrocytes in a mouse model of cerebral amyloid angiopathy.

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