NeuroTimone Facility (PFNT)

The PFNT Facility is a coherent set of exploration tools in neurobiology allowing research at the molecular, cellular and integrated levels.

News

  1. Listening to our molecular clocks

    During the NeuroStories event, held on Monday October 7 at the Faculty of Medicine, Anne-Marie François Bellan gave a remarkable stand up on how our body vibrates to the rhythm of internal chronometers called circadian clocks. She also explained how the molecular clock uses small corpuscles and cell space to make our genes rhythm. The video of his speech and those of the other six speakers will be available very soon.

  2. Prof. D. Figarella-Branger, who belongs to the cIMPACT-NOW Working Committee, attended to the last meeting of the consortium in Utrecht (16-17 september).

    The cIMPACT-NOW Working Committee is the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy. cIMPACT-NOW  was created in late 2016 —following publication of the 2016 Updated 4th Edition of the World Health Organization (WHO) Classification of Tumours of the Central Nervous System— to provide a forum to evaluate and recommend proposed changes to future CNS tumor classifications.

  3. Three members of INP presented their work on Glioma during the 14th EANO annual meeting held in Lyon (19 - 22 September, 2019)

    During the 14th EANO annual meeting 3 members of INP team #8 presented their work on Glioma in a plenary conference «CDKN2A homozygous deletion is a strong adverse prognosis factor in diffuse malignant IDHmutant gliomas» Dominique Figarella Branger, a short talk «Plasmatic differential scanning fluorimetry profiles discriminate glioma patients from healthy controls» Emeline Tabouret and two posters «P11.06: Non epigenetic effect of vorinostat in glioblastoma cells» and «EB1-dependant long survival of glioblastoma cancer stem-like cells tumor

  4. Nadia Merad Coliac and Maxime Bonnet joined the NOSE team

    Nadia Merad Coliac, plastic designer, joined the NOSE (Nasal Olfactory Stemness and Epigenesis) team, as an Associate researcher. At the crossroads of several disciplines, she develops an experimental work of art and science, in the field of bioluminescence. She is considering a therapeutic application in patients with autism spectrum disorders (ASD). Recently, Nadia published Lumière vivante - Théorie et pratique de la bioluminescence (Living light - theory and use of bioluminescence) - L’Harmattan eds.

  5. New publication from the GlioME Team (INP team 8) in Cancers pointing at A2B5 as an attractive therapeutic target for glioblastomas.
  6. F. Devred and E. Tabouret presented their research work at the annual Canceropole PACA meeting
  7. INP team 8 and 9 and PINT members presented their work at the 4th French Microtubule Network

    INP team 8 and 9 and PINT members being part of the French Microtubule Network, several members presented their work at the 4th French Microtubule Network gathering in Rennes on the 1srt and 2nd july 2019, in the  "Microtubules and their regulators : new therapeutic targets" session and the "Microtubules, assembly and regulation" session. Pascale Barbier presented her work "", Raphael Berges his work "Proscillaridin A exerts anti-tumor effects through"GSK3 activation and alteration of microtubule dynamics in glioblastoma" and François Devred a new method of "Functional screening of therapeutic agents and targets using nanoDSF "

  8. CNRS and Aix-Marseille University sign Agreement with the SME Vect-Horus on the intellectual property

    An article entitled "Le CNRS et Aix-Marseille Université signent un accord avec la PME Vect-Horus sur la propriété intellectuelle",  published in the CNRS Innovation Letter of 20 June 2019 and relayed by the INSB site, features the agreement signed by CNRS, AMU and Vect-Horus establishing the intellectual property rights regime and the exploitation of patents.

Pages

INP in numbers

  • 126 members
  • 44 researchers
  • 48 research assistants
  • 12 post-docs
  • 11 PhD

 

Listening to our molecular clocks

During the NeuroStories event, held on Monday October 7 at the Faculty of Medicine, Anne-Marie François Bellan gave a remarkable stand up on how our body vibrates to the rhythm of internal chronometers called circadian clocks. She also explained how the molecular clock uses small corpuscles and cell space to make our genes rhythm. The video of his speech and those of the other six speakers will be available very soon.

English

Prof. D. Figarella-Branger, who belongs to the cIMPACT-NOW Working Committee, attended to the last meeting of the consortium in Utrecht (16-17 september).

The cIMPACT-NOW Working Committee is the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy. cIMPACT-NOW  was created in late 2016 —following publication of the 2016 Updated 4th Edition of the World Health Organization (WHO) Classification of Tumours of the Central Nervous System— to provide a forum to evaluate and recommend proposed changes to future CNS tumor classifications.

Undefined

Three members of INP presented their work on Glioma during the 14th EANO annual meeting held in Lyon (19 - 22 September, 2019)

During the 14th EANO annual meeting 3 members of INP team #8 presented their work on Glioma in a plenary conference «CDKN2A homozygous deletion is a strong adverse prognosis factor in diffuse malignant IDHmutant gliomas» Dominique Figarella Branger, a short talk «Plasmatic differential scanning fluorimetry profiles discriminate glioma patients from healthy controls» Emeline Tabouret and two posters «P11.06: Non epigenetic effect of vorinostat

Undefined

Nadia Merad Coliac and Maxime Bonnet joined the NOSE team

Nadia Merad Coliac, plastic designer, joined the NOSE (Nasal Olfactory Stemness and Epigenesis) team, as an Associate researcher. At the crossroads of several disciplines, she develops an experimental work of art and science, in the field of bioluminescence. She is considering a therapeutic application in patients with autism spectrum disorders (ASD). Recently, Nadia published Lumière vivante - Théorie et pratique de la bioluminescence (Living light - theory and use of bioluminescence) - L’Harmattan eds.

English

New publication from the GlioME Team (INP team 8) in Cancers pointing at A2B5 as an attractive therapeutic target for glioblastomas.

F. Devred and E. Tabouret presented their research work at the annual Canceropole PACA meeting

Many members of the INP attended the annual Canceropole PACA meeting in the Palais des Congrès of St Raphaël on the 4th and 5th of july. In the frame of the translational research call, F. Devred (INP team 9) & E. Tabouret (INP team 8) presented the results and perspective of their project "Next generation plasma profiling of gliomas using nanoDSF: toward a new prognostic and monitoring tool"

Full program available here.

Undefined

INP team 8 and 9 and PINT members presented their work at the 4th French Microtubule Network

INP team 8 and 9 and PINT members being part of the French Microtubule Network, several members presented their work at the 4th French Microtubule Network gathering in Rennes on the 1srt and 2nd july 2019, in the  "Microtubules and their regulators : new therapeutic targets" session and the "Microtubules, assembly and regulation" session.

Undefined

CNRS and Aix-Marseille University sign Agreement with the SME Vect-Horus on the intellectual property

An article entitled "Le CNRS et Aix-Marseille Université signent un accord avec la PME Vect-Horus sur la propriété intellectuelle",  published in the CNRS Innovation Letter of 20 June 2019 and relayed by the INSB site, features the agreement signed by CNRS, AMU and Vect-Horus establishing the intellectual property rights regime and the exploitation of patents.

Undefined

The GlioME team published a new article in Stem Cells and one eye-catch figure of their paper was selected for the cover image of the June journal issue!

Our last work on IAPs : "Inhibitor of Apoptosis Proteins (IAPs) Determines Glioblastoma Stem‐Like Cell Fate in an Oxygen‐Dependent Manner" is now published in Stem Cells. We highlighted that pharmacological inhibition of IAPs by Smac mimetic GDC-0152 was able to decrease glioblastoma stem-like cells viability in hypoxia by decreasing cell proliferation and increasing apoptosis through ATR and TNFα pathways

English

INP researchers and students massively attended NeuroFrance 2019

During the last NeuroFrance congress held from May 22 to 24, 2019 at the Palais des Congrès in Marseille, the INP distinguished itself through 20 posters, 4 oral communications, and 1 symposium moderation, not to mention the organization of the "Art in Mind" exhibition, showing not only the richness and quality of his research but also his open-mindedness. 

English

Next seminars

8 Nov 2019 14:30

Christophe Picard - " Facteurs de susceptibilité génétique à la sclérose en plaques. Où en sommes-nous ?"

Faculté de médecine de la Timone, Amphithéatre 4

Christophe Picard est chercheur à l'EFS et fait partie de la Team 5 - Neuro-inflammation and Multiple Sclerosis.

15 Nov 2019 14:30

Vect-Horus presentation

Faculté de médecine de la Timone, Amphithéatre 5

VECT-HORUS is a biotechnology company which is member of the INP in the context of a “Laboratoire Commun de Recherche” as the basis for a solid academic-industry partnership.

22 Nov 2019 14:30

Aurélie Tchoghandjian - "Pan-cellular effects of Smac mimetics in Glioblastomas"

Faculté de médecine de la Timone, Amphithéatre CERIMED

Aurélie Tchoghandjian is CRCN in the Team 8 - GlioME: Gliomagenesis and MicroEnvironment.

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